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社区住宿和职业安置中成年智障者使用精神药物和抗惊厥药物的情况。

Psychotropic and anticonvulsant drug use by mentally retarded adults across community residential and vocational placements.

作者信息

Martin J E, Agran M

出版信息

Appl Res Ment Retard. 1985;6(1):33-49. doi: 10.1016/s0270-3092(85)80020-5.

Abstract

The prevalence of psychotropic and anticonvulsant drug use across a comprehensive continuum of community programs for mentally retarded adults was examined. Psychotropic and/or anticonvulsant drugs were administered to 48% of the sample. The hypnotic, antidepressant, antimanic, and anxiolytic medications were used by 6%-12%, the anticonvulsants by 48%, and the neuroleptics by 66% of those who were prescribed psychotropic drugs. Mildly mentally retarded persons used more neuroleptic, manic, and antidepressant medication. Severely and profoundly mentally retarded individuals used more anxiolytics and hypnotic drugs. Psychotropic and anticonvulsant drug intake varied little by sex. However, an institutional history was associated with higher levels of drug use. Seventy percent of those with an institutional history were prescribed drugs; in comparison, only 27% of those without such a history used medication. The percentage of individuals who used psychotropic and anticonvulsant drugs increased dramatically as both the vocational and residential placements became more restrictive. Possible toxic behavioral effects of psychotropic and anticonvulsant medication upon habilitative efforts were discussed. Future research issues were suggested.

摘要

对一系列针对成年智障者的社区项目中精神药物和抗惊厥药物的使用情况进行了调查。样本中有48%的人使用了精神药物和/或抗惊厥药物。在使用精神药物的人群中,6%-12%的人使用了催眠药、抗抑郁药、抗躁狂药和抗焦虑药,48%的人使用了抗惊厥药,66%的人使用了抗精神病药。轻度智障者使用更多的抗精神病药、抗躁狂药和抗抑郁药。重度和极重度智障者使用更多的抗焦虑药和催眠药。精神药物和抗惊厥药物的摄入量在性别上差异不大。然而,有机构生活史与更高的药物使用水平相关。有机构生活史的人中有70%被开了药;相比之下,没有这种生活史的人中只有27%使用药物。随着职业和居住安置限制的增加,使用精神药物和抗惊厥药物的人的比例急剧上升。讨论了精神药物和抗惊厥药物对康复努力可能产生的毒性行为影响。提出了未来的研究问题。

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