氨基酸向TOR激活的信号传导：Vam6作为Gtr1鸟苷酸交换因子发挥作用。
Amino acid signaling to TOR activation: Vam6 functioning as a Gtr1 GEF.
作者信息
Li Li, Guan Kun-Liang
机构信息
Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, 92093, USA.
出版信息
Mol Cell. 2009 Sep 11;35(5):543-5. doi: 10.1016/j.molcel.2009.08.010.
PMID:19748348
Abstract
In this issue of Molecular Cell, Binda et al. identify Vam6/Vps39 as a guanine nucleotide exchange factor for Gtr1, a Rag family GTPase, to promote TORC1 activation in response to amino acids.
摘要
在本期《分子细胞》杂志中，宾达等人将Vam6/Vps39鉴定为Rag家族GTP酶Gtr1的鸟嘌呤核苷酸交换因子，以促进TORC1在响应氨基酸时的激活。
Zotero 插件