宿主-病原体关系中的宿主耐受性与抗性及微生物毒力
Host tolerance versus resistance and microbial virulence in the host-pathogen equation.
作者信息
Ferrandon Dominique
机构信息
UPR 9022 du CNRS, Université de Strasbourg, Institut de Biologie Moléculaire et Cellulaire, Strasbourg Cedex, France.
出版信息
Cell Host Microbe. 2009 Sep 17;6(3):203-5. doi: 10.1016/j.chom.2009.08.010.
PMID:19748463
Abstract
To deal with an infection, the organism resorts to nonmutually exclusive strategies: resistance, that is, neutralization or destruction of the pathogen; or tolerance, the ability to withstand damages inflicted by the pathogen or by host defense. In this issue of Cell Host & Microbe, Shinzawa et al. (2009) identify p38-mediated phagocytic encapsulation as a potential tolerance mechanism.
摘要
为应对感染，生物体采取多种并非相互排斥的策略：抗性，即中和或破坏病原体；或者耐受性，即承受病原体或宿主防御造成损害的能力。在本期《细胞宿主与微生物》中，Shinzawa等人（2009年）确定p38介导的吞噬包裹是一种潜在的耐受机制。
Zotero 插件