儿童流感暴发期间分离出的禽副黏病毒的来源。

The source of avian paramyxoviruses isolated during an outbreak of influenza among children.

作者信息

Yakhno M A, Govorkova E A, Kubínova I, Ivanova V T, Stumpa A, Tůmová B

机构信息

D. I. Ivanovsky Institute of Virology, Academy of Medical Sciences of U.S.S.R., Prague, Czechoslovakia.

出版信息

Acta Virol. 1990 Apr;34(2):184-7.

PMID:1975980

Abstract

In 1986 five avian paramyxovirus (PMV) strains were isolated in embryonated chicken eggs from sick children with influenza. The strains were identified as PMV-2 serotype due to the close antigenic relationships between their HN-proteins and of the reference PMV-2 strains isolated from different birds all over the world. No seroconversion to the isolates was found in the sick children, however, HI-antibodies were detected in hen's sera, eggs of which were used for the new strains isolation. The possible origin of isolated PMV-2 viruses is discussed.

摘要

1986年，从患流感的病童体内采集的鸡蛋中分离出5株禽副粘病毒（PMV）毒株。由于这些毒株的血凝素神经氨酸酶（HN）蛋白与从世界各地不同鸟类中分离出的参考PMV - 2毒株具有密切的抗原关系，因此被鉴定为PMV - 2血清型。然而，在患病儿童中未发现针对这些分离株的血清转化现象，不过，在用于分离新毒株的母鸡血清中检测到了血凝抑制（HI）抗体。本文还讨论了分离出的PMV - 2病毒的可能来源。