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用于同种异体移植的储存骨的生物负荷评估。

Bioburden assessment of banked bone used for allografts.

作者信息

Varettas Kerry, Taylor Peter

机构信息

South Eastern Area Laboratory Services, St. George Hospital, Sydney, NSW, Australia.

出版信息

Cell Tissue Bank. 2011 Feb;12(1):37-43. doi: 10.1007/s10561-009-9154-z. Epub 2009 Sep 17.

DOI:10.1007/s10561-009-9154-z
PMID:19760122
Abstract

Allograft bone is commonly used in reconstructive orthopaedic surgery and needs to be assessed for bioburden before transplant. The Microbiology Department of the South Eastern Area Laboratory Services (SEALS), located at the St. George Hospital, Sydney, has provided this service to the New South Wales (NSW) Bone Bank. This study reviewed the organisms isolated from femoral head allografts of living donors from the NSW Bone Bank over a 7-year period. It was found that growth was reported from 4.9% of samples with the predominant organism being coagulase-negative staphylococci. This review will focus on the micro-organisms isolated, the interaction of the laboratory with the bone bank, the relevance of the bioburden assessment in the overall quality process and patient safety.

摘要

同种异体骨常用于骨科重建手术,移植前需要对其生物负荷进行评估。位于悉尼圣乔治医院的东南地区实验室服务部(SEALS)微生物科为新南威尔士州(NSW)骨库提供了这项服务。本研究回顾了新南威尔士州骨库7年间从活体供体股骨头同种异体骨中分离出的微生物。结果发现,4.9%的样本有生长报告,主要微生物为凝固酶阴性葡萄球菌。本综述将聚焦于分离出的微生物、实验室与骨库的相互作用、生物负荷评估在整体质量控制过程及患者安全中的相关性。

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