同种异体骨移植：谢菲尔德的经验。
Allograft bone transplantation: a Sheffield experience.
作者信息
Khan M T, Stockley I, Ibbotson C
机构信息
Department of Orthopaedics, Northern General Hospital, Sheffield.
出版信息
Ann R Coll Surg Engl. 1998 Mar;80(2):150-3.
There has been an increase in demand for allograft bone in recent years. This type of bone provides an excellent material to fill in bony defects, but could be associated with an incidence of infection. Any newly established tissue bank has to meet the very stringent criteria to process and store bone and maintain a donor and recipient database to avoid transmission of infection. The Sheffield Tissue Bank has been functioning since 1989 and until 1993 has provided bone allografts to 220 patients; these have been used mainly to reconstruct defects at revision hip and knee arthroplasty and for scoliosis surgery. There have been no cases of disease transmission and the rate of infection has been reduced by strict screening protocols. This paper outlines our experience, problems and success with human bone banking.
近年来，同种异体骨的需求有所增加。这种类型的骨为填充骨缺损提供了优质材料，但可能会有感染发生率。任何新成立的组织库都必须满足非常严格的标准来处理和储存骨，并维护供体和受体数据库以避免感染传播。谢菲尔德组织库自1989年开始运作，截至1993年已为220名患者提供了同种异体骨；这些主要用于髋关节和膝关节翻修置换术中的缺损重建以及脊柱侧弯手术。没有疾病传播的病例，并且通过严格的筛查方案降低了感染率。本文概述了我们在人体骨库方面的经验、问题和成功之处。
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