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点燃作为人类癫痫的一种模型。

Kindling as a model of human epilepsy.

作者信息

McIntyre Dan C, Gilby Krista L

机构信息

Department of Psychology, Institute of Neuroscience, Carleton University, Ottawa, Ontario, Canada.

出版信息

Can J Neurol Sci. 2009 Aug;36 Suppl 2:S33-5.

PMID:19760897
Abstract

The evidence supporting the suggestion that kindling is a good model of human temporal lobe epilepsy is briefly reviewed. Parallels between the human condition, involving both partial and secondarily generalized seizures, and kindling in rats and other animals are drawn and contrasted.

摘要

简要回顾了支持点燃是人类颞叶癫痫良好模型这一观点的证据。对人类情况(包括部分性发作和继发性全身性发作)与大鼠及其他动物的点燃之间的相似之处进行了比较和对比。

相似文献

1
Kindling as a model of human epilepsy.点燃作为人类癫痫的一种模型。
Can J Neurol Sci. 2009 Aug;36 Suppl 2:S33-5.
2
Sensory stimulation reduces seizure severity but not afterdischarge duration of partial seizures kindled in the hippocampus at threshold intensities.感觉刺激可降低癫痫发作的严重程度,但在阈值强度下,对海马体中点燃的部分性癫痫发作的放电后持续时间无影响。
Neurosci Lett. 2005 Nov 4;388(1):33-8. doi: 10.1016/j.neulet.2005.06.028.
3
MRI compatible electrodes for the induction of amygdala kindling in rats.用于诱导大鼠杏仁核点燃的磁共振成像兼容电极
J Neurosci Methods. 2006 Jul 15;155(1):72-6. doi: 10.1016/j.jneumeth.2005.12.024. Epub 2006 Feb 8.
4
The effect of generalized absence seizures on the progression of kindling in the rat.全身性失神发作对大鼠点燃进程的影响。
Epilepsia. 2007;48 Suppl 5:150-6. doi: 10.1111/j.1528-1167.2007.01303.x.
5
Unilateral low-frequency stimulation of central piriform cortex delays seizure development induced by amygdaloid kindling in rats.对大鼠梨状皮质中央区进行单侧低频刺激可延缓杏仁核点燃诱导的癫痫发作发展。
Neuroscience. 2006;138(4):1089-96. doi: 10.1016/j.neuroscience.2005.12.006. Epub 2006 Jan 20.
6
Effects of the novel antiepileptic drug lacosamide on the development of amygdala kindling in rats.新型抗癫痫药物拉科酰胺对大鼠杏仁核点燃发展的影响。
Epilepsia. 2006 Nov;47(11):1803-9. doi: 10.1111/j.1528-1167.2006.00818.x.
7
Stimulation of the superior cerebellar peduncle during the development of amygdaloid kindling in rats.大鼠杏仁核点燃发展过程中对小脑上脚的刺激。
Brain Res. 2004 Jun 4;1010(1-2):151-5. doi: 10.1016/j.brainres.2004.03.015.
8
[Epilepsy. Recent advances in the knowledge of its physiopathology].[癫痫。其生理病理学知识的最新进展]
Gac Med Mex. 1989 Sep-Oct;125(9-10):249-69.
9
Parahippocampal networks, intractability, and the chronic epilepsy of kindling.
Adv Neurol. 2006;97:77-83.
10
Amygdaloid kindling is anxiogenic but fails to alter object recognition or spatial working memory in rats.杏仁核点燃会引发焦虑,但不会改变大鼠的物体识别或空间工作记忆。
Epilepsy Behav. 2008 Jul;13(1):52-61. doi: 10.1016/j.yebeh.2008.02.007. Epub 2008 Mar 11.

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The Medial Septum as a Potential Target for Treating Brain Disorders Associated With Oscillopathies.内侧隔区作为治疗与振荡病相关脑疾病的潜在靶点。
Front Neural Circuits. 2021 Jul 8;15:701080. doi: 10.3389/fncir.2021.701080. eCollection 2021.
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Activity-dependent changes in excitability of perirhinal cortex networks in vitro.体外梨状周围皮质神经网络兴奋性的活动依赖性变化。
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Electrical brain stimulation for epilepsy.电刺激治疗癫痫。
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