Bekyarova Elena, Ni Yingchun, Malarkey Erik B, Montana Vedrana, McWilliams Jared L, Haddon Robert C, Parpura Vladimir
Center for Nanoscale Science and Engineering, Departments of Chemisty and Chemical & Environmental Engineering, University of California, Riverside, CA 92521, USA.
J Biomed Nanotechnol. 2005 Mar 1;1(1):3-17. doi: 10.1166/jbn.2005.004.
Due to their electrical, chemical, mechanical and thermal properties, carbon nanotubes are one of the most promising materials for the electronics, computer and aerospace industries. Here, we discuss their properties in the context of future applications in biotechnology and biomedicine. The purification and chemical modification of carbon nanotubes with organic, polymeric and biological molecules are discussed. Additionally we review their uses in biosensors, assembly of structures and devices, scanning probe microscopy and as substrates for neuronal growth. We note that additional toxicity studies of carbon nanotubes are necessary so that exposure guidelines and safety regulations can be established in a timely manner.
由于其电学、化学、机械和热学性质,碳纳米管是电子、计算机和航空航天工业中最具前景的材料之一。在此,我们将在生物技术和生物医学未来应用的背景下讨论它们的性质。文中讨论了碳纳米管与有机分子、聚合物分子和生物分子的纯化及化学修饰。此外,我们还综述了它们在生物传感器、结构和器件组装、扫描探针显微镜以及作为神经元生长底物方面的应用。我们指出,有必要对碳纳米管进行更多的毒性研究,以便及时制定暴露指南和安全法规。