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利用调频电场和通道几何效应增强电动驱动的微流体T型混合器

Enhancement of electrokinetically driven microfluidic T-mixer using frequency modulated electric field and channel geometry effects.

作者信息

Yan Deguang, Yang Chun, Miao Jianmin, Lam Yeecheong, Huang Xiaoyang

机构信息

School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, Singapore.

出版信息

Electrophoresis. 2009 Sep;30(18):3144-52. doi: 10.1002/elps.200900162.

Abstract

This study reports improved electrokinetically driven microfluidic T-mixers to enhance their mixing efficiency. Enhancement of electrokinetic microfluidic T-mixers is achieved using (i) an active approach of utilizing a pulsating EOF, and (ii) a passive approach of using the channel geometry effect with patterned blocks. PDMS-based electrokinetic T-mixers of different designs were fabricated. Experimental measurements were carried out using Rhodamine B to examine the mixing performance and the micro-particle image velocimetry technique to characterize the electrokinetic flow velocity field. Scaling analysis provides an effective frequency range of applied AC electric field. Results show that for a T-mixer of 10 mm mixing length, utilizing frequency modulated electric field and channel geometry effects can increase the mixing efficiency from 50 to 90%. In addition, numerical simulations were performed to analyze the mixing process in the electrokinetic T-mixers with various designs. The simulation results were compared with the experimental data, and reasonable agreement was found.

摘要

本研究报告了改进的电动驱动微流体T型混合器,以提高其混合效率。电动微流体T型混合器的增强是通过以下方式实现的:(i)利用脉动电渗流的主动方法,以及(ii)使用带有图案化块的通道几何效应的被动方法。制造了不同设计的基于聚二甲基硅氧烷(PDMS)的电动T型混合器。使用罗丹明B进行实验测量,以检查混合性能,并使用微粒子图像测速技术来表征电动流速度场。标度分析提供了所施加交流电场的有效频率范围。结果表明,对于混合长度为10毫米的T型混合器,利用调频电场和通道几何效应可将混合效率从50%提高到90%。此外,还进行了数值模拟,以分析各种设计的电动T型混合器中的混合过程。将模拟结果与实验数据进行了比较,发现了合理的一致性。

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