Nai Jiacheng, Zhang Feng, Dong Peng, Fu Ting, Ge Anle, Xu Shuang, Pan Yanqiao
Hubei Key Laboratory of Mechanical Transmission and Manufacturing Engineering, Wuhan University of Science and Technology, Wuhan 430081, China.
Key Laboratory of Metallurgical Equipment and Control Technology, Ministry of Education, Wuhan University of Science and Technology, Wuhan 430081, China.
Micromachines (Basel). 2023 Feb 26;14(3):545. doi: 10.3390/mi14030545.
As an important part of lab-on-a-chip and micro-total analysis systems, micromixers have a wide range of applications in biochemical analysis, pharmaceutical preparation and material synthesis. In the work, a novel rhombic separation and recombination micromixer with baffles was presented to further improve the performance of the micromixer and study the effect of multiple structural parameters on mixing. The effects of the rhombic angle, the width ratio of sub-channel and the size and relative positions of baffles on the mixing index were studied numerically at different Reynolds numbers (), and the sensitivity of the mixing index to various structures was also investigated. The results showed that the mixing index increased with the subchannel's width ratio and slowly decreased after reaching the peak value in the range of from 0.1 to 60. The maximum mixing index appeared when the width ratio was 6.5. The pressure drops in the microchannel were proportional to the width ratio. The mixing effect can be further improved by adding baffle structure to asymmetric rhombus micromixer, and more baffle quantity and larger baffle height were beneficial to the improvement of the mixing index. The research results can provide reference and new ideas for the structure design of passive micromixers.
作为芯片实验室和微全分析系统的重要组成部分，微混合器在生化分析、药物制备和材料合成等领域有着广泛的应用。在这项工作中，提出了一种新型带挡板的菱形分离与重组微混合器，以进一步提高微混合器的性能，并研究多个结构参数对混合的影响。在不同雷诺数（）下，数值研究了菱形角度、子通道宽度比以及挡板尺寸和相对位置对混合指数的影响，同时还研究了混合指数对各种结构的敏感性。结果表明，混合指数随着子通道宽度比的增加而增大，在0.1至60的范围内达到峰值后缓慢下降。当宽度比为6.5时，混合指数出现最大值。微通道中的压降与宽度比成正比。在不对称菱形微混合器中添加挡板结构可进一步提高混合效果，更多的挡板数量和更大的挡板高度有利于混合指数的提高。研究结果可为被动式微混合器的结构设计提供参考和新思路。
