Department of Head and Neck Surgery, Erasto Gaertner Hospital Curitiba, Paraná, Brazil.
Med Oral Patol Oral Cir Bucal. 2010 Jan 1;15(1):e32-7. doi: 10.4317/medoral.15.e32.
The aim of this study was to evaluate the diagnostic accuracy, sensitivity and specificity of fine needle aspiration biopsies (FNAB) of salivary gland tumours performed at the Erasto Gaertner Hospital over the course of a four year period.
A retrospective study was carried out between 2001-2005 to review the cases of patients with salivary gland tumours who had undergone pre-operative FNAB and had been diagnosed during post-operative histopathology examination.
A total of 106 cases of salivary gland tumours were considered for this study, but 27 cases (25.5%) of the samples were considered unsatisfactory for analysis. The sensitivity, specificity and accuracy were calculated considering only the 79 benign and malignant cases in which FNAB provided sufficient samples for analysis. Based on these data, the value of sensitivity was 68.2% (15/22), specificity was 87.7% (50/57), accuracy was 82.3% (65/79), positive predictive value was 68.2% (15/22) and negative predictive value was 87.7% (50/57).
Despite the high rate of inadequate samples obtained in the FNAB in this study, the technique offers high specificity, accuracy and acceptable sensitivity.
本研究旨在评估在 Erasto Gaertner 医院进行的为期四年的唾液腺肿瘤细针抽吸活检（FNAB）的诊断准确性、敏感性和特异性。
本回顾性研究于 2001-2005 年进行，以回顾接受术前 FNAB 并在术后组织病理学检查中诊断为唾液腺肿瘤的患者的病例。
共有 106 例唾液腺肿瘤病例被纳入本研究，但由于样本不足，27 例（25.5%）的样本不适合分析。仅考虑到 79 例 FNAB 提供了足够样本进行分析的良性和恶性病例，计算了敏感性、特异性和准确性。根据这些数据，敏感性为 68.2%（15/22），特异性为 87.7%（50/57），准确性为 82.3%（65/79），阳性预测值为 68.2%（15/22），阴性预测值为 87.7%（50/57）。
尽管本研究中 FNAB 获得的样本不足率较高，但该技术具有较高的特异性、准确性和可接受的敏感性。
