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细针穿刺活检对涎腺肿瘤的准确性、敏感性和特异性:一项2006年至2011年的回顾性研究

Accuracy, Sensitivity and Specificity of Fine Needle Aspiration Biopsy for Salivary Gland Tumors: A Retrospective Study from 2006 to 2011.

作者信息

Silva William P P, Stramandinoli-Zanicotti Roberta T, Schussel Juliana L, Ramos Gyl H A, Ioshi Sergio O, Sassi Laurindo M

机构信息

Erasto Gaertner Hospital, Curitiba, Brazil. Email:

出版信息

Asian Pac J Cancer Prev. 2016 Nov 1;17(11):4973-4976. doi: 10.22034/APJCP.2016.17.11.4973.

Abstract

Objective: This article concerns evaluation of the sensitivity, specificity and accuracy of FNAB for pre-surgical diagnosis of benign and malignant lesions of major and minor salivary glands of patients treated in the Department of Head and Neck Surgery of Erasto Gartner Hospital. Methods: This retrospective study analyzed medical records from January 2006 to December 2011 from patients with salivary gland lesions who underwent preoperative FNAB and, after surgical excision of the lesion, histopathological examination. Results: The study had a cohort of 130 cases, but 34 cases (26.2%) were considered unsatisfactory regarding cytology analyses. Based on the data, sensitivity was 66.7% (6/9), specificity was 81.6% (71/87), accuracy was 80.2% (77/96), the positive predictive value was 66,7% (6/9) and the negative predictive value was 81.6% (71/87). Conclusion: Despite the high rate of inadequate samples obtained in the FNAB in this study the technique offers high specificity, accuracy and acceptable sensitivity.

摘要

目的

本文旨在评估在埃拉斯托·加特纳医院头颈外科接受治疗的患者中,细针穿刺抽吸活检(FNAB)对涎腺良恶性病变术前诊断的敏感性、特异性和准确性。方法:这项回顾性研究分析了2006年1月至2011年12月期间涎腺病变患者的病历,这些患者均接受了术前FNAB,并在病变手术切除后进行了组织病理学检查。结果:该研究队列中有130例病例,但34例(26.2%)的细胞学分析结果不理想。基于这些数据,敏感性为66.7%(6/9),特异性为81.6%(71/87),准确性为80.2%(77/96),阳性预测值为66.7%(6/9),阴性预测值为81.6%(71/87)。结论:尽管本研究中FNAB获取的样本不合格率较高,但该技术具有较高的特异性、准确性和可接受的敏感性。

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