Ivanova Antoaneta, Mikhova Bozhanka, Najdenski Hristo, Tsvetkova Iva, Kostova Ivanka
Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Nat Prod Commun. 2009 Aug;4(8):1059-62.
The chemical composition of fresh flowers from Allium ursinum (ramsons, bear's garlic, wild garlic) growing in Bulgaria has been studied. Thymidine (1), adenosine (2), astragalin (kaempferol-3-O-beta-D-glucopyranoside (3), kaempferol-3-O-beta-D-glucopyranosyl-7-O-beta-D-glucopyranoside (4), kaempferol-3-O-beta-D-neohesperoside (5), and kaempferol-3-O-beta-D-neohesperoside-7-O-beta-D-glucopyranoside (6) were isolated from the n-butanol extract and identified by different spectroscopic and spectrometric methods. Thymine (7), uridine (8), uracil (9) and 5-chloro-uridine (10) were detected in the same extract by GC-MS. This is the first report of the occurrence of 1, 2, 4, 7 - 10 in the flowers of A. ursinum. GC-MS of the volatile components of fresh flowers and leaves from the same plant revealed a high content of sulfur compounds, some of which are reported for the first time for A. ursinum. The antimicrobial activities of extracts from fresh flowers and leaves of A. ursinum have been tested; some extracts exhibited moderate antifungal properties.
对生长在保加利亚的熊葱（ramsons、熊蒜、野蒜）鲜花的化学成分进行了研究。从正丁醇提取物中分离出胸苷（1）、腺苷（2）、紫云英苷（山奈酚-3-O-β-D-吡喃葡萄糖苷）（3）、山奈酚-3-O-β-D-吡喃葡萄糖基-7-O-β-D-吡喃葡萄糖苷（4）、山奈酚-3-O-β-D-新橙皮糖苷（5）和山奈酚-3-O-β-D-新橙皮糖苷-7-O-β-D-吡喃葡萄糖苷（6），并通过不同的光谱和光谱测定方法进行了鉴定。通过气相色谱-质谱联用（GC-MS）在同一提取物中检测到胸腺嘧啶（7）、尿苷（8）、尿嘧啶（9）和5-氯尿苷（10）。这是首次报道熊葱花朵中存在1、2、4、7 - 10。对同一植株鲜花和叶片挥发性成分的GC-MS分析显示，硫化合物含量很高，其中一些是首次报道存在于熊葱中。对熊葱鲜花和叶片提取物的抗菌活性进行了测试；一些提取物表现出中等程度的抗真菌特性。
