Harrison M R, Adzick N S, Jennings R W, Duncan B W, Rosen M A, Filly R A, Goldberg J D, deLorimier A A, Golbus M S
Fetal Treatment Program, University of California, San Francisco 94143-0570.
Lancet. 1990 Oct 20;336(8721):965-7. doi: 10.1016/0140-6736(90)92420-m.
In 2 fetuses with congenital cystic adenomatoid malformation (CCAM) with hydrops, in-utero resection of the enlarged pulmonary lobe reduced mediastinal shift and allowed expansion of normal lung tissue in both cases. In case 1, the 27-week-gestation fetus died from severe hydrops after premature delivery. In case 2, fetal CCAM resection was completed at 23 weeks' gestation. At 30 weeks a girl was delivered with no evidence of pulmonary hypoplasia. Fetal surgery can now be entertained for otherwise fatal space-occupying intrathoracic lesions.
