Department of Neurosurgery, University of Virginia, Charlottesville, VA 22908, USA.
Spine (Phila Pa 1976). 2009 Jul 15;34(16):1693-8. doi: 10.1097/BRS.0b013e3181ac5fcd.
Retrospective review of a prospective, multicenter study.
The purpose of this study was to assess the prevalence and severity of leg pain in adults with scoliosis and to assess whether surgery significantly improved leg pain compared with nonoperative management.
Patients with adult scoliosis characteristically present with pain. The presence of leg pain is an independent predictor of a patient's choice for operative over nonoperative care.
Data were extracted from a prospective, multicenter database for adult spinal deformity. At enrollment and follow-up, patients complete the Oswestry Disability Index (ODI) and assessment of leg pain using the numerical rating scale (NRS) score, with 0 and 10 representing no pain and unbearable pain, respectively. Plan for operative or nonoperative treatment was made at enrollment. The vast majority of adult scoliosis patients seen in our surgical clinics have received nonoperative therapies and are being seen for a surgical evaluation. Patients are counseled regarding operative and nonoperative management options and are in general encouraged to maximize nonoperative treatments.
Two hundred eight (64%) of 326 adults with scoliosis had leg pain at presentation (mean NRS score = 4.7). Ninety-six patients with leg pain (46%) were managed operatively and 112 were treated nonoperatively. The operative group had higher baseline mean NRS score for leg pain (5.4 vs. 4.1, P < 0.001) and higher mean ODI (41 vs. 30, P < 0.001). At 2-year follow-up, nonoperative patients had no significant change in ODI or NRS score for leg pain (P = 0.2). In contrast, at 2-year follow-up surgically treated patients had significant improvement in mean NRS score for leg pain (5.4 vs. 2.2, P < 0.001) and ODI (41 vs. 24, P < 0.001). Compared with nonsurgically treated patients, at 2-year follow-up operative patients had lower mean NRS score for leg pain (2.2 vs. 3.8, P < 0.001) and mean ODI (24 vs. 31, P = 0.005).
Despite having started with significantly greater leg pain and disability, surgically treated patients at 2-year follow-up had significantly less leg pain and disability than nonoperatively treated patients. Surgical treatment has the potential to provide significant improvement of leg pain in adults with scoliosis.
前瞻性、多中心研究的回顾性分析。
本研究旨在评估成人脊柱侧凸患者腿部疼痛的发生率和严重程度,并评估手术治疗与非手术治疗相比是否能显著改善腿部疼痛。
成人脊柱侧凸患者通常会出现疼痛。腿部疼痛的存在是患者选择手术治疗而非非手术治疗的独立预测因素。
数据取自成人脊柱畸形的前瞻性、多中心数据库。在入组和随访时,患者使用 Oswestry 残疾指数(ODI)和数字评分量表(NRS)评估腿部疼痛,其中 0 分代表无痛,10 分代表无法忍受的疼痛。入组时制定手术或非手术治疗计划。我们外科诊所中绝大多数成人脊柱侧凸患者都接受过非手术治疗,并正在接受手术评估。患者接受手术和非手术治疗方案的咨询,并普遍鼓励他们最大限度地接受非手术治疗。
208 名(64%)326 名脊柱侧凸成人患者就诊时存在腿部疼痛(平均 NRS 评分=4.7)。96 名腿部疼痛患者(46%)接受手术治疗,112 名接受非手术治疗。手术组腿部疼痛的基线平均 NRS 评分较高(5.4 比 4.1,P<0.001),ODI 平均值也较高(41 比 30,P<0.001)。在 2 年随访时,非手术组患者的 ODI 或腿部疼痛的 NRS 评分没有明显变化(P=0.2)。相比之下,在 2 年随访时,接受手术治疗的患者腿部疼痛的 NRS 评分(5.4 比 2.2,P<0.001)和 ODI(41 比 24,P<0.001)均有显著改善。与非手术治疗的患者相比,在 2 年随访时,手术治疗的患者腿部疼痛的 NRS 评分(2.2 比 3.8,P<0.001)和 ODI(24 比 31,P=0.005)较低。
尽管手术组患者腿部疼痛和残疾的起始程度明显更高,但在 2 年随访时,手术组患者的腿部疼痛和残疾程度明显低于非手术组患者。手术治疗有可能显著改善成人脊柱侧凸患者的腿部疼痛。