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老年退行性脊柱侧凸患者健康状况和残疾的标准化评估与手术治疗决策。

Standardized measures of health status and disability and the decision to pursue operative treatment in elderly patients with degenerative scoliosis.

机构信息

Department of Neurological Surgery, University of Virginia Medical Center, Charlottesville, Virginia, USA.

出版信息

Neurosurgery. 2010 Jan;66(1):42-7; discussion 47. doi: 10.1227/01.NEU.0000361999.29279.E6.

Abstract

OBJECTIVE

Treatment decision making in elderly patients with degenerative scoliosis is complex. Although most patients can be adequately treated with nonoperative therapies, a subset ultimately elects for surgical treatment. However, the factors that govern this transition are poorly understood. The objective of this study was to assess whether standardized measures of health status and disability may be useful in distinguishing those patients who elect for surgical treatment.

METHODS

This study is a retrospective review of a prospective database of 139 consecutive patients aged older than 60 years (mean = 70 years), with degenerative scoliosis treated by a single surgeon. Patients with severe symptoms who had failed multimodality nonoperative care were considered for surgical intervention. The Scoliosis Research Society Questionnaire (SRS-30), 12-Item Short Form Health Survey (SF-12), Oswestry Disability Index (ODI) surveys, and Charlson Comorbidity Index (CCI) were collected at the time of presentation and compared between the operative and nonoperative groups.

RESULTS

There were no statistically significant differences between the operative and nonoperative groups in terms of age and major radiographic parameters. Significant differences between the operative and nonoperative groups were found for all 3 self-assessment survey results, with those electing for operative intervention reporting worse scores for ODI (54 versus 40; P = .001), SRS-30 (2.7 versus 3.0; P = .01), SF-12 physical component summary (23 versus 29; P = .01), and SF-12 mental component summary (46 versus 52; P = .03). Unexpectedly, patients treated surgically had a higher level of comorbidity as measured by the CCI (2.0 versus 1.3; P = .003).

CONCLUSION

Self-assessments of health and disability distinguish elderly patients with degenerative scoliosis electing for surgery compared with those who continue nonoperative therapies. Standardized measures of health status and disability may be useful in identifying patients nearing the threshold of crossing over to surgical treatment.

摘要

目的

老年退行性脊柱侧凸患者的治疗决策较为复杂。大多数患者可通过非手术治疗得到充分治疗,但仍有一部分患者最终选择手术治疗。然而,目前对于决定患者选择手术治疗的因素尚缺乏了解。本研究旨在评估健康状况和残疾的标准化测量指标是否有助于区分选择手术治疗的患者。

方法

本研究为回顾性分析,纳入了 139 例由同一位医生治疗的年龄大于 60 岁(平均年龄 70 岁)的退行性脊柱侧凸患者的前瞻性数据库。有严重症状且经多模式非手术治疗失败的患者被考虑进行手术干预。在就诊时收集 Scoliosis Research Society 问卷(SRS-30)、12 项简明健康调查问卷(SF-12)、Oswestry 残疾指数(ODI)和 Charlson 合并症指数(CCI),并比较手术组和非手术组的结果。

结果

手术组和非手术组在年龄和主要影像学参数方面无统计学差异。但在所有 3 项自我评估调查结果中,手术组与非手术组存在显著差异,选择手术治疗的患者 ODI(54 分比 40 分;P =.001)、SRS-30(2.7 分比 3.0 分;P =.01)、SF-12 生理成分评分(23 分比 29 分;P =.01)和 SF-12 心理成分评分(46 分比 52 分;P =.03)均较差。出乎意料的是,CCI 测量的手术组患者的合并症水平更高(2.0 分比 1.3 分;P =.003)。

结论

与继续接受非手术治疗的患者相比,退行性脊柱侧凸老年患者选择手术治疗时的健康和残疾自我评估结果更差。健康状况和残疾的标准化测量指标可能有助于识别即将达到手术治疗阈值的患者。

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