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Why are oseltamivir and zanamivir effective against the newly emerged influenza A virus (A/H1N1)?

作者信息

Yu Kunqian, Luo Cheng, Qin Guangrong, Xu Zhijian, Li Ning, Liu Hong, Shen Xu, Ma Jianpeng, Wang Qinghua, Yang Caiguang, Zhu Weiliang, Jiang Hualiang

出版信息

Cell Res. 2009 Oct;19(10):1221-4. doi: 10.1038/cr.2009.111. Epub 2009 Sep 22.

DOI:10.1038/cr.2009.111
PMID:19770846
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7091778/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6d0/7091778/d1aff9adc707/41422_2009_Article_BFcr2009111_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6d0/7091778/d1aff9adc707/41422_2009_Article_BFcr2009111_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6d0/7091778/d1aff9adc707/41422_2009_Article_BFcr2009111_Fig1_HTML.jpg

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PLoS Pathog. 2008 Jul 25;4(7):e1000103. doi: 10.1371/journal.ppat.1000103.
3
Another look at the molecular mechanism of the resistance of H5N1 influenza A virus neuraminidase (NA) to oseltamivir (OTV).
将高性能计算应用于药物发现和分子模拟。
Natl Sci Rev. 2016 Mar;3(1):49-63. doi: 10.1093/nsr/nww003. Epub 2016 Jan 11.
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Post-Glycosylation Modification of Sialic Acid and Its Role in Virus Pathogenesis.唾液酸的糖基化后修饰及其在病毒致病机制中的作用
Vaccines (Basel). 2019 Nov 1;7(4):171. doi: 10.3390/vaccines7040171.
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Computational study on new natural polycyclic compounds of H1N1 influenza virus neuraminidase.针对 H1N1 流感病毒神经氨酸酶的新型天然多环化合物的计算研究。
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