A.V. Nikolaev Institute of Inorganic Chemistry, Siberian Branch--Russian Academy of Science (SB RAS), 630090, Novosibirsk, Russia.
Toxicol Mech Methods. 2009 Jan;19(1):1-18. doi: 10.1080/15376510801891310.
The purpose of this investigation is to analyze 20 nails in individuals (and several persons) for the definition of how chemical elements distribute from nail to nail. The aim was to determine whether it will be rightful to take only one nail for the elemental analysis for the diagnostic of human state in future or not? Another purpose of the research is to analyze the elemental content of nails in temporal dynamic (in several persons). Analytical determinations of 20 nails of nine donors (healthy persons), nails of both hands and both feet were carried out. The analysis was performed by SRXRF. Symmetry of the elemental distribution in nails of right and left hands and right and left feet was found. The analysis of the distribution of chemical elements on the total area of a nail (55 points) was performed. The nail cutaway reflects adequately the distribution of several chemical elements over the nail plate area. In this study the elemental concentrations in nails of three donors in a 6-month period was determined. This study found the content of the chemical elements in donors' nails changes with time, individually.
本研究的目的是分析 20 个指甲(以及多个人的指甲),以确定化学元素从一个指甲到另一个指甲的分布情况。目的是确定将来是否可以只取一个指甲进行元素分析来诊断人体状况?研究的另一个目的是分析指甲在时间动态(多个人)中的元素含量。对 9 名供体(健康人)的 20 个指甲、双手和双脚的指甲进行了分析。采用同步辐射 X 射线荧光(SRXRF)进行分析。发现了右手和左手以及右脚和左脚指甲中元素分布的对称性。对指甲总面积(55 个点)上化学元素的分布进行了分析。指甲的切层可以充分反映指甲板区域内几个化学元素的分布情况。在这项研究中,我们确定了三名供体在 6 个月期间的指甲中的元素浓度。本研究发现,供体指甲中的元素含量随时间而变化,因人而异。