Sureda Antoni, Bibiloni Maria Del Mar, Julibert Alicia, Aparicio-Ugarriza Raquel, Palacios-Le Blé Gonzalo, Pons Antoni, Gonzalez-Gross Marcela, Tur Josep A
Research Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands, Palma de Mallorca, Spain.
CIBEROBN (Physiopathology of Obesity and Nutrition CB12/03/30038), Instituto de Salud Carlos III, Madrid, Spain.
PLoS One. 2017 Oct 6;12(10):e0185318. doi: 10.1371/journal.pone.0185318. eCollection 2017.
The aim was to assess the trace element contents in toenails of older adults and its association with regular physical activity. Cross-sectional multicentre study in Spain, collecting data from a random sample of 380 participants (54% female) aged 55-80 years (men) and 60-80 years (women) with no previously documented cardiovascular disease. Physical activity performed was measured using the Minnesota Leisure-time Physical Activity Questionnaire. The 25 most inactive and 25 most active individuals for each sex were selected for this study (final sample n = 100). Anthropometric measurements were performed and toenail samples collected for calcium (Ca), chromium (Cr), iron (Fe), cobalt (Co), nickel (Ni), zinc (Zn), selenium (Se) and mercury (Hg) analysis. Significant differences between sexes were reported in Ca concentrations, women having lower concentrations than men. No differences were reported in trace element contents between active and inactive men. Active women showed higher Ca, Cr, Fe, Co, and Zn and lower Hg contents than their inactive peers (all p<0.05). Inactive women showed lower Ca and Co levels (735.0 mg/kg and 4.5 μg/kg, respectively) than inactive men (1170.0 mg/kg and 7.9 μg/kg, respectively). Active women had lower Ca and higher levels of Cr (936.0 mg/kg and 1230.0 μg/kg, respectively) than active men (1070.0 mg/kg and 522.0 μg/kg, respectively). The present data added new information on the element contents in toenails of healthy Spanish older adults. The concentration of trace elements was similar in both sexes except for Ca which were lower in women. The trace element contents in women's toenails, but not in men, were markedly influenced by physical activity, with higher levels of Ca and Fe and lower Hg among active females.
目的是评估老年人脚趾甲中的微量元素含量及其与定期体育活动的关联。在西班牙进行的一项横断面多中心研究，从380名参与者（54%为女性）的随机样本中收集数据，这些参与者年龄在55 - 80岁（男性）和60 - 80岁（女性），且此前无心血管疾病记录。使用明尼苏达休闲时间身体活动问卷来测量所进行的体育活动。为该研究选取了每种性别中最不活跃的25人和最活跃的25人（最终样本n = 100）。进行了人体测量，并采集脚趾甲样本用于钙（Ca）、铬（Cr）、铁（Fe）、钴（Co）、镍（Ni）、锌（Zn）、硒（Se）和汞（Hg）分析。报告显示，钙浓度存在性别差异，女性的浓度低于男性。活跃男性和不活跃男性之间的微量元素含量无差异。活跃女性的钙、铬、铁、钴和锌含量高于不活跃的同龄人，汞含量低于不活跃的同龄人（所有p<0.05）。不活跃女性的钙和钴水平（分别为735.0毫克/千克和4.5微克/千克）低于不活跃男性（分别为1170.0毫克/千克和7.9微克/千克）。活跃女性的钙含量低于活跃男性（分别为936.0毫克/千克和1070.0毫克/千克），铬含量高于活跃男性（分别为1230.0微克/千克和522.0微克/千克）。目前的数据为健康西班牙老年人脚趾甲中的元素含量增添了新信息。除钙外，微量元素浓度在两性中相似，女性的钙含量较低。女性脚趾甲中的微量元素含量受体育活动的显著影响，但男性不受影响，活跃女性的钙和铁含量较高，汞含量较低。
