决策的神经生物学：共识与争议

The neurobiology of decision: consensus and controversy.

作者信息

Kable Joseph W, Glimcher Paul W

机构信息

Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA.

出版信息

Neuron. 2009 Sep 24;63(6):733-45. doi: 10.1016/j.neuron.2009.09.003.

DOI:10.1016/j.neuron.2009.09.003

PMID:19778504

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2765926/

Abstract

We review and synthesize recent neurophysiological studies of decision making in humans and nonhuman primates. From these studies, the basic outline of the neurobiological mechanism for primate choice is beginning to emerge. The identified mechanism is now known to include a multicomponent valuation stage, implemented in ventromedial prefrontal cortex and associated parts of striatum, and a choice stage, implemented in lateral prefrontal and parietal areas. Neurobiological studies of decision making are beginning to enhance our understanding of economic and social behavior as well as our understanding of significant health disorders where people's behavior plays a key role.

摘要

我们回顾并综合了近期关于人类和非人类灵长类动物决策的神经生理学研究。从这些研究中，灵长类动物选择的神经生物学机制的基本轮廓开始显现。现已确定该机制包括一个多成分评估阶段，在腹内侧前额叶皮层和纹状体的相关部位实现，以及一个选择阶段，在外侧前额叶和顶叶区域实现。决策的神经生物学研究开始增进我们对经济和社会行为的理解，以及对人们行为起关键作用的重大健康障碍的理解。