Jha N
Department of Pharmacology, Kathmandu Medical College, Sinamangal, KTM.
Kathmandu Univ Med J (KUMJ). 2004 Jan-Mar;2(1):28-34.
A prospective study of various coronary and contributory risk factors in urban and rural diabetic population is presented. For the coronary risk factors, smoking prevalence was high for urban diabetics (27%), also high TC levels (57%), and low levels of HDL cholesterol (17%) were comparatively greater in urban diabetics. Prevalence of hypertension was higher, (40%) in rural diabetics. High LDL levels were (>130mg/dl) were observed in 20% of rural subjects and 47% of urban diabetics. High TG levels (34%) were seen in rural diabetics. 54% of urban diabetics were centrally obese and 57% were obese from the rural study site. From this study, it was seen that, illiteracy percentage was found to be higher in rural subjects. Also, greater number of people (70%) were in inadequate status for the needed patient awareness. 77% of patients belonging to the rural study area were found to be unaware for the hypoglycaemia. Low patient compliance was seen in urban diabetics as compared to their rural counterparts, and 34% of patients belonging to both study sites were found to have no knowledge for diabetic complications. High total cholesterol was found to be the commonest lipid profile abnormality in this study. Second commonest lipid abnormality was high LDL levels. Low HDL cholesterol was found to be more commonly in patients of age > 60 years than <60 years (21.42% vs. 18.18%). More female patients were overweight and obese as compared to male (33.33% vs. 19.23%). A Large population of diabetics was found to have a sedentary lifestyle. Rural patients were progressing towards more coronary risk factors as compared to the urban ones, mainly with the lipid profile abnormalities. Although our type 2 diabetic patients share similar coronary risk factors as compared to diabetic patients from different countries, our type 2 patients have got high prevalence of hypertension. Male diabetics had high prevalence of smoking habits.
本文呈现了一项针对城乡糖尿病患者各种冠心病及相关危险因素的前瞻性研究。在冠心病危险因素方面，城市糖尿病患者的吸烟率较高（27%），总胆固醇（TC）水平也较高（57%），而高密度脂蛋白胆固醇（HDL-C）水平较低（17%），城市糖尿病患者中的这些情况相对更为突出。农村糖尿病患者的高血压患病率较高（40%）。20%的农村受试者和47%的城市糖尿病患者低密度脂蛋白（LDL）水平较高（>130mg/dl）。农村糖尿病患者的甘油三酯（TG）水平较高（34%）。54%的城市糖尿病患者为中心性肥胖，农村研究地点的肥胖率为57%。从这项研究可以看出，农村受试者的文盲率较高。此外，更多的人（70%）对患者所需的知晓情况不足。农村研究区域77%的患者对低血糖不知情。与农村糖尿病患者相比，城市糖尿病患者的患者依从性较低，两个研究地点34%的患者对糖尿病并发症一无所知。在本研究中，高总胆固醇是最常见的血脂异常。第二常见的血脂异常是高LDL水平。HDL-C低在年龄>60岁的患者中比<60岁的患者更常见（21.42%对18.18%）。与男性相比，超重和肥胖的女性患者更多（33.
