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土耳其成年人中心血管代谢危险因素的最佳腰高比切点。

Optimal waist:height ratio cut-off point for cardiometabolic risk factors in Turkish adults.

机构信息

Division of Endocrinology and Metabolism, Department of Medicine, Private Gayrettepe Florence Nightingale Hospital, Istanbul, Turkey.

出版信息

Public Health Nutr. 2010 Apr;13(4):488-95. doi: 10.1017/S1368980009991637. Epub 2009 Sep 28.

DOI:10.1017/S1368980009991637
PMID:19781128
Abstract

OBJECTIVE

To identify the optimal waist:height ratio (WHtR) cut-off point that discriminates cardiometabolic risk factors in Turkish adults.

DESIGN

Cross-sectional study. Hypertension, dyslipidaemia, diabetes, metabolic syndrome score >or=2 (presence of two or more metabolic syndrome components except for waist circumference) and at least one risk factor (diabetes, hypertension or dyslipidaemia) were categorical outcome variables. Receiver-operating characteristic (ROC) curves were prepared by plotting 1 - specificity on the x-axis and sensitivity on the y-axis. The WHtR value that had the highest Youden index was selected as the optimal cut-off point for each cardiometabolic risk factor (Youden index = sensitivity + specificity - 1).

SETTING

Turkey, 2003.

SUBJECTS

Adults (1121 women and 571 men) aged 18 years and over were examined.

RESULTS

Analysis of ROC coordinate tables showed that the optimal cut-off value ranged between 0.55 and 0.60 and was almost equal between men and women. The sensitivities of the identified cut-offs were between 0.63 and 0.81, the specificities were between 0.42 and 0.71 and the accuracies were between 0.65 and 0.73, for men and women. The cut-off point of 0.59 was the most frequently identified value for discrimination of the studied cardiometabolic risk factors. Subjects classified as having WHtR >or= 0.59 had significantly higher age and sociodemographic multivariable-adjusted odds ratios for cardiometabolic risk factors than subjects with WHtR < 0.59, except for diabetes in men.

CONCLUSIONS

We show that the optimal WHtR cut-off point to discriminate cardiometabolic risk factors is 0.59 in Turkish adults.

摘要

目的

确定最佳腰围身高比(WHtR)切点,以区分土耳其成年人的心血管代谢危险因素。

设计

横断面研究。高血压、血脂异常、糖尿病、代谢综合征评分≥2(除腰围外,至少有两种代谢综合征成分存在)和至少有一种危险因素(糖尿病、高血压或血脂异常)为分类结局变量。绘制 1-特异性在 x 轴上,敏感性在 y 轴上的接收者操作特征(ROC)曲线。选择具有最高 Youden 指数的 WHtR 值作为每个心血管代谢危险因素的最佳截断点(Youden 指数=敏感性+特异性-1)。

地点

土耳其,2003 年。

对象

检查了年龄在 18 岁及以上的成年人(1121 名女性和 571 名男性)。

结果

ROC 坐标表分析表明,最佳截断值范围在 0.55 到 0.60 之间,在男性和女性之间几乎相等。确定的截断值的敏感性在 0.63 到 0.81 之间,特异性在 0.42 到 0.71 之间,准确性在 0.65 到 0.73 之间,男性和女性。区分所研究的心血管代谢危险因素时,0.59 是最常确定的截断值。WHtR≥0.59 的受试者与 WHtR<0.59 的受试者相比,年龄较大,社会人口统计学多变量调整后的心血管代谢危险因素比值较高,男性除外糖尿病。

结论

我们表明,区分土耳其成年人心血管代谢危险因素的最佳 WHtR 截断值为 0.59。

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