Rachelefsky Gary S
Allergy and Immunology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Clin Cornerstone. 2009;9(3):9-19. doi: 10.1016/s1098-3597(09)80008-2.
The National Asthma Education and Prevention Program's (NAEPP) revised guidelines, the Expert Panel Report 3 (EPR-3), published in 2007, represents a shift in the approach to asthma: the EPR-3 recommends that clinicians think of asthma as a chronic disease with an inflammatory basis. EPR-3 guidelines also represent a shift in the treatment paradigm for asthma in line with the shift in approach: although symptomatic relief is still necessary, the primary goal of asthma treatment is now long-term control, with the aim of minimizing exacerbation frequency and severity and limiting possible permanent airway damage that can result from frequent asthma exacerbations. To help clinicians implement the new EPR-3 guidelines into daily practice, the NAEPP's Guidelines Implementation Panel has identified 6 key action-focused recommendations. This article describes those recommendations and the evidence supporting them.
国家哮喘教育与预防计划(NAEPP)于2007年发布的修订指南《专家小组报告3》(EPR - 3)代表了哮喘治疗方法的转变:EPR - 3建议临床医生将哮喘视为一种具有炎症基础的慢性疾病。EPR - 3指南还代表了哮喘治疗模式的转变,与治疗方法的转变相一致:尽管缓解症状仍然必要,但哮喘治疗的主要目标现在是长期控制,目的是将发作频率和严重程度降至最低,并限制频繁哮喘发作可能导致的永久性气道损伤。为帮助临床医生将新的EPR - 3指南应用于日常实践,NAEPP指南实施小组确定了6项以行动为重点的关键建议。本文描述了这些建议及其支持证据。