China Animal Health & Epidemiology Center, Qingdao 266032, China.
J Virol Methods. 2010 Feb;163(2):186-9. doi: 10.1016/j.jviromet.2009.09.013. Epub 2009 Sep 23.
Subtype H9 avian influenza viruses (AIVs) circulating in China have aroused concerns for their impact on poultry and risk to public health. In this report, three surveys of the viruses were reported, and the hemagglutinin gene of 55 strains of the viruses isolated in China in 2007-2009 was sequenced and analyzed. The results indicated that the prevalence of the viruses was rising in China, and most of the H9 AIVs circulating in the past decade in China belonged to sublineage h9.4.2. The viruses isolated in China in 2007-2009 were a little different from previous strains (genetic distances >7.1%). Meanwhile, a presumably predominant clade of the viruses circulating in China in 2007-2009 was identified. Mutation analysis suggested that the viruses have become of greater risk to public health in recent years.
在中国流行的 H9 亚型禽流感病毒（AIVs）引起了人们对其对家禽的影响和对公众健康的风险的关注。在本报告中，报道了三次针对这些病毒的调查，并对中国 2007-2009 年分离的 55 株病毒的血凝素基因进行了测序和分析。结果表明，病毒在中国的流行率正在上升，过去十年在中国流行的大多数 H9 AIVs 属于 h9.4.2 亚系。中国 2007-2009 年分离的病毒与以前的毒株略有不同（遗传距离>7.1%）。同时，确定了中国 2007-2009 年流行的病毒的一个可能占主导地位的分支。突变分析表明，近年来这些病毒对公众健康的风险更大。
