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飞秒激光辅助准分子原位角膜磨镶术与准分子上皮下原位角膜磨镶术矫正近视的比较。

Comparison between femtosecond laser-assisted sub-Bowman keratomileusis vs laser subepithelial keratectomy to correct myopia.

作者信息

de Benito-Llopis Laura, Teus Miguel A, Gil-Cazorla Raquel, Drake Pilar

机构信息

Vissum Madrid, C/ Santa Hortensia, Madrid, Spain.

出版信息

Am J Ophthalmol. 2009 Dec;148(6):830-6.e1. doi: 10.1016/j.ajo.2009.07.008. Epub 2009 Sep 24.

DOI:10.1016/j.ajo.2009.07.008
PMID:19781686
Abstract

PURPOSE

To compare femtosecond laser sub-Bowman keratomileusis (FSBK) vs laser subepithelial keratectomy (LASEK) to correct myopia.

DESIGN

Retrospective, nonrandomized, interventional, comparative case series.

METHODS

Two thousand one hundred and eight eyes were included in the study. We compared 1,072 eyes treated with FSBK vs 1,036 eyes treated with LASEK with or without mitomycin C (MMC). Visual and refractive results were evaluated 1 day, 1 week, and 1 and 3 months postoperatively.

RESULTS

Preoperative mean sphere and best spectacle-corrected visual acuity (BSCVA) were -3.93 diopters (D) vs -3.87 D (P = .5) and 1.12 vs 1.12 (P = .8) in FSBK and LASEK, respectively. Uncorrected visual acuity (UCVA) was 0.92 vs 0.62, 0.98 vs 0.78, 0.96 vs 0.91, and 1.06 vs 1.03 in FSBK and LASEK, respectively, at 1 day, 1 week, and 1 and 3 months after surgery (P < .01 for all comparisons). Three months postoperatively, BSCVA was 1.13 and 1.10, respectively (P = .001). At that moment, 20 eyes (1.93%) in the LASEK group vs 9 eyes (0.84%) in the FSBK group had lost 2 or more lines of BSCVA. Ten eyes (0.96%) in the LASEK group gained 2 or more lines of BSCVA, whereas 3 eyes (0.28%) in the FSBK group gained 2 lines. Six months postoperatively, only 2 LASEK eyes (0.19%) showed loss of 2 or more lines of BSCVA, compared to 3 FSBK-treated eyes (0.28%).

CONCLUSION

Both FSBK and LASEK are safe and effective procedures to correct myopia. Slightly better visual and refractive results were observed in FSBK-treated eyes in a 3-month follow-up.

摘要

目的

比较飞秒激光基质内准分子原位角膜磨镶术(FSBK)与上皮下准分子激光角膜切削术(LASEK)矫正近视的效果。

设计

回顾性、非随机、干预性、比较性病例系列研究。

方法

本研究纳入2108只眼。我们比较了1072只接受FSBK治疗的眼睛与1036只接受LASEK治疗(使用或不使用丝裂霉素C[MMC])的眼睛。在术后1天、1周、1个月和3个月评估视力和屈光结果。

结果

术前,FSBK组和LASEK组的平均球镜度数分别为-3.93屈光度(D)和-3.87 D(P = 0.5),最佳矫正视力(BSCVA)分别为1.12和1.12(P = 0.8)。术后1天、1周、1个月和3个月时,FSBK组和LASEK组的裸眼视力(UCVA)分别为0.92对0.62、0.98对0.78、0.96对0.91和1.06对1.03(所有比较P < 0.01)。术后3个月,BSCVA分别为1.13和1.10(P = 0.001)。此时,LASEK组有20只眼(1.93%)BSCVA下降2行或更多,而FSBK组有9只眼(0.84%)。LASEK组有10只眼(0.96%)BSCVA提高2行或更多,而FSBK组有3只眼(0.28%)提高2行。术后6个月,LASEK组仅有2只眼(0.19%)BSCVA下降2行或更多,而FSBK组有3只眼(0.28%)。

结论

FSBK和LASEK都是矫正近视的安全有效方法。在3个月的随访中,FSBK治疗的眼睛在视力和屈光方面的结果略好。

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