McAndrew Lisa M, Napolitano Melissa A, Albrecht Anna, Farrell Nancy C, Marcus Bess H, Whiteley Jessica A
Dept. of Veterans Affairs NJ Healthcare System, War Related Illness and Injury Center, 385 Tremont Ave #129, East Orange, NJ 07018, United States.
Maturitas. 2009 Oct 20;64(2):119-25. doi: 10.1016/j.maturitas.2009.08.009. Epub 2009 Sep 24.
The relationship between enhanced physical activity and decreased menopause symptoms is equivocal. In this study we sought to better understand this relationship by examining the association of physical activity to different symptom domains and by examining mediating and moderating variables.
Women participating in a randomized control trial on physical activity were given a menopause symptom measure (MENQOL) at follow-up. Of the 280 women participating, 113 (mean age=52) reported having symptoms they attributed to menopause. Regression analyses were run to examine if change in physical activity predicted fewer symptoms. Exercise self-efficacy was examined as a mediator and depressive symptoms as a moderator.
An increase in physical activity from baseline was found to be related to reporting fewer total menopause symptoms (beta=-0.22, p=.02). When the total menopause symptoms score was examined by domain, increased physical activity was found to be related to reporting fewer general symptoms attributed to menopause (psychosocial (beta=-0.18, p=.05) and physical (beta=-0.23, p=.01)), but had no effect on specific symptoms of menopause (vasomotor and sexual). Exercise self-efficacy was found to mediate the relationship between increased physical activity and total, physical and psychosocial menopause symptoms. Finally, for individuals with high depressive symptoms, those who increased physical activity the most reported fewer sexual symptoms of menopause.
This study suggests that physical activity participation is associated with lower general symptom reporting as opposed to specifically impacting menopause symptoms. Further, exercise self-efficacy mediates the relationship between physical activity and general menopause symptoms, suggesting a psychological pathway.
增强体力活动与减轻更年期症状之间的关系尚不明确。在本研究中，我们试图通过研究体力活动与不同症状领域的关联以及中介和调节变量，来更好地理解这种关系。
参与一项关于体力活动的随机对照试验的女性在随访时接受了更年期症状测量（MENQOL）。在参与的280名女性中，113名（平均年龄 = 52岁）报告有她们认为是更年期引起的症状。进行回归分析以检验体力活动的变化是否能预测症状减少。将运动自我效能作为中介变量进行检验，将抑郁症状作为调节变量进行检验。
发现与基线相比，体力活动增加与报告的更年期症状总数减少有关（β = -0.22，p = 0.02）。当按领域检查更年期症状总分时，发现体力活动增加与报告的归因于更年期的一般症状减少有关（心理社会方面（β = -0.18，p = 0.05）和身体方面（β = -0.23，p = 0.01）），但对更年期的特定症状（血管舒缩和性方面）没有影响。发现运动自我效能介导了体力活动增加与更年期总体、身体和心理社会症状之间的关系。最后，对于抑郁症状严重的个体，体力活动增加最多的人报告的更年期性症状较少。
本研究表明，参与体力活动与较低的一般症状报告相关，而不是特别影响更年期症状。此外，运动自我效能介导了体力活动与更年期一般症状之间的关系，提示了一条心理途径。
