Department of Radiology, Northwestern University, Chicago, IL 60611, USA.
Magn Reson Imaging. 2010 Feb;28(2):195-9. doi: 10.1016/j.mri.2009.08.001. Epub 2009 Sep 24.
Contrast-enhanced magnetic resonance angiography (MRA) is a promising technique for coronary artery imaging. The blood signal changes during the contrast injection will result in image artifacts, blurring and relatively low signal-to-noise ratio, when the k-space segments from different cardiac cycles are combined to reconstruct the final image as "time averaged." Thus, it is important to acquire data during maximal blood signal enhancement for first-pass, contrast-enhanced MRA, and relatively high temporal resolution is required. This work demonstrated the feasibility of highly constrained backprojection reconstruction for time-resolved, contrast-enhanced coronary MRA. With this method, the temporal resolution can be increased. In addition, coronary artery images around blood signal enhancement peak have significantly improved contrast-to-noise ratio and suppressed artifacts compared to the composite images which were collected during a much longer acquisition time during substantial blood signal changes.
对比增强磁共振血管造影（MRA）是一种很有前途的冠状动脉成像技术。当来自不同心动周期的 K 空间段被组合以重建最终的“时间平均”图像时，对比剂注射期间的血液信号变化会导致图像伪影、模糊和相对较低的信噪比。因此，对于首次通过、对比增强 MRA，重要的是在最大血液信号增强期间获取数据，并且需要相对较高的时间分辨率。这项工作证明了高约束反向投影重建在时间分辨、对比增强冠状动脉 MRA 中的可行性。通过这种方法，可以提高时间分辨率。此外，与在血液信号变化较大的较长采集时间内采集的组合图像相比，在血液信号增强峰值周围的冠状动脉图像具有显著改善的对比噪声比和抑制的伪影。
