将细胞周期与组蛋白修饰联系起来：Dot1、G1/S期以及循环性K79甲基化修饰二价体
Linking the cell cycle to histone modifications: Dot1, G1/S, and cycling K79me2.
作者信息
Mellor Jane
机构信息
Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
出版信息
Mol Cell. 2009 Sep 24;35(6):729-30. doi: 10.1016/j.molcel.2009.09.010.
PMID:19782019
Abstract
In a recent issue of Molecular Cell, Schulze et al. (2009) described distinct distributions and regulation of Dot1-dependent methylation states at lysine 79 on histone H3 and showed cell-cycle regulation of K79 dimethylation on genes expressed during the G1/S phase.
摘要
在最近一期的《分子细胞》杂志上，舒尔茨等人（2009年）描述了组蛋白H3赖氨酸79位点上Dot1依赖的甲基化状态的不同分布和调控，并展示了G1/S期表达基因上K79二甲基化的细胞周期调控。
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