Department of Basic Sciences, Faculty of Dental Sciences, University of Peradeniya, Peradeniya, Sri Lanka.
Arch Oral Biol. 2009 Nov;54(11):1016-21. doi: 10.1016/j.archoralbio.2009.09.001. Epub 2009 Sep 26.
Interglobular dentine (IGD) is an area of poorly mineralized dentine matrix. It has been reported that there is an association between the retraction of odontoblast processes (OP) and the formation of IGD. A variation of the extent of OP has been described depending on the region of the tooth and age. This study aimed to find out the regional distribution of IGD in human teeth to observe any association between the extent of OP and the pattern of distribution of IGD. Ground sections were prepared from 52 extracted permanent teeth and the presence of IGD was observed in different regions of the crown and the root. The highest occurrence of IGD was found in the cervical and middle thirds followed by intercuspal, and coronal third in the crown. Statistical analysis of data depicted that the occurrence of IGD differed according to the region of the tooth. In roots, the highest occurrence of IGD was seen in the cervical third followed by the middle third. Previous reports have shown that OP extend up to the dentine-enamel junction in the coronal region and to the inner one-third of the cervical region. The varied pattern of distribution of IGD in the crown and root observed in our results corresponds to the above findings. Therefore, it is reasonable to surmise that there is an association between the distribution of IGD and the extent of OP. This allows us to confer that IGD tends to form in areas where OP do not extend to the dentine-enamel junction.
球间牙本质（IGD）是一种矿化程度较低的牙本质基质区域。有报道称，成牙本质细胞突起（OP）的退缩与 IGD 的形成之间存在关联。根据牙齿的区域和年龄，OP 的程度存在变化。本研究旨在找出人类牙齿中 IGD 的区域分布，以观察 OP 的程度与 IGD 分布模式之间的任何关联。从 52 颗拔除的恒牙中制备磨片，并观察牙冠和牙根不同区域 IGD 的存在情况。结果发现，牙冠的颈中三分之一、牙尖交错区和冠中三分之一区域 IGD 的发生率最高。数据的统计分析表明，IGD 的发生情况因牙齿区域而异。在牙根中，IGD 发生率最高的部位是颈三分之一，其次是中三分之一。先前的报告表明，OP 在牙冠区延伸至牙釉质牙本质界，在颈区延伸至内三分之一。我们的研究结果观察到 IGD 在牙冠和牙根中的分布模式各不相同，这与上述发现相符。因此，可以合理地推测 IGD 的分布与 OP 的程度之间存在关联。这使我们能够得出结论，IGD 倾向于在 OP 未延伸到牙釉质牙本质界的区域形成。
