Laboratory of Epidemiology and Biometry, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA.
Drug Alcohol Depend. 2010 Feb 1;107(1):31-8. doi: 10.1016/j.drugalcdep.2009.08.019. Epub 2009 Sep 25.
The relative severity of the 11 DSM-IV alcohol use disorder (AUD) criteria are represented by their severity threshold scores, an item response theory (IRT) model parameter inversely proportional to their prevalence. These scores can be used to create a continuous severity measure comprising the total number of criteria endorsed, each weighted by its relative severity.
This paper assesses the validity of the severity ranking of the 11 criteria and the overall severity score with respect to known AUD correlates, including alcohol consumption, psychological functioning, family history, antisociality, and early initiation of drinking, in a representative population sample of U.S. past-year drinkers (n=26,946).
The unadjusted mean values for all validating measures increased steadily with the severity threshold score, except that legal problems, the criterion with the highest score, was associated with lower values than expected. After adjusting for the total number of criteria endorsed, this direct relationship was no longer evident. The overall severity score was no more highly correlated with the validating measures than a simple count of criteria endorsed, nor did the two measures yield different risk curves. This reflects both within-criterion variation in severity and the fact that the number of criteria endorsed and their severity are so highly correlated that severity is essentially redundant.
Attempts to formulate a scalar measure of AUD will do as well by relying on simple counts of criteria or symptom items as by using scales weighted by IRT measures of severity.
DSM-IV 酒精使用障碍(AUD)11 项标准的相对严重程度由其严重程度阈值得分表示,这是一种与流行率成反比的项目反应理论(IRT)模型参数。这些分数可用于创建一个连续的严重程度衡量标准,包括所认可的标准总数,每个标准都根据其相对严重程度加权。
本文评估了 11 项标准的严重程度排序和整体严重程度评分在已知 AUD 相关性方面的有效性,包括酒精摄入量、心理功能、家族史、反社会行为和饮酒的早期开始,在一个具有代表性的美国过去一年饮酒者的人群样本中(n=26,946)。
除了具有最高得分的法律问题外,所有验证性措施的未调整均值都随着严重程度阈值得分的增加而稳步增加,而法律问题与预期值相比则较低。在调整了所认可标准的总数后,这种直接关系就不再明显。总体严重程度评分与验证性措施的相关性并不高于简单地计算所认可标准的数量,而且这两个措施也没有产生不同的风险曲线。这反映了严重程度在标准内的差异,以及所认可标准的数量及其严重程度高度相关,以至于严重程度本质上是多余的。
尝试制定 AUD 的标量衡量标准,通过简单地计算标准或症状项目,或者通过使用 IRT 严重程度衡量标准加权的量表,都可以取得同样的效果。