Alcohol Epidemiologic Data System, NIAAA/NIH, CSR Incorporated, 2107 Wilson Boulevard, Arlington, VA 22201, USA.
Alcohol Clin Exp Res. 2009 May;33(5):868-78. doi: 10.1111/j.1530-0277.2009.00910.x. Epub 2009 Mar 11.
There is limited information on the validity of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) alcohol use disorders (AUD) symptom criteria among adolescents in the general population. The purpose of this study is to assess the DSM-IV AUD symptom criteria as reported by adolescent and adult drinkers in a single representative sample of the U.S. population aged 12 years and older. This design avoids potential confounding due to differences in survey methodology when comparing adolescents and adults from different surveys.
A total of 133,231 current drinkers (had at least 1 drink in the past year) aged 12 years and older were drawn from respondents to the 2002 to 2005 National Surveys on Drug Use and Health. DSM-IV AUD criteria were assessed by questions related to specific symptoms occurring during the past 12 months. Factor analytic and item response theory models were applied to the 11 AUD symptom criteria to assess the probabilities of symptom item endorsements across different values of the underlying trait.
A 1-factor model provided an adequate and parsimonious interpretation for the 11 AUD criteria for the total sample and for each of the gender-age groups. The MIMIC model exhibited significant indication for item bias among some criteria by gender, age, and race/ethnicity. Symptom criteria for "tolerance,""time spent," and "hazardous use" had lower item thresholds (i.e., lower severity) and low item discrimination, and they were well separated from the other symptoms, especially in the 2 younger age groups (12 to 17 and 18 to 25). "Larger amounts,""cut down,""withdrawal," and "legal problems" had higher item thresholds but generally lower item discrimination, and they tend to exhibit greater dispersion at higher AUD severity, particularly in the youngest age group (12 to 17).
Findings from the present study do not provide support for the 2 separate DSM-IV diagnoses of alcohol abuse and dependence among either adolescents or adults. Variations in criteria severity for both abuse and dependence offer support for a dimensional approach to diagnosis which should be considered in the ongoing development of DSM-V.
在普通人群的青少年中,关于《精神疾病诊断与统计手册》第四版(DSM-IV)酒精使用障碍(AUD)症状标准的有效性信息有限。本研究的目的是评估在一个代表性的美国 12 岁及以上人群中,青少年和成年饮酒者报告的 DSM-IV AUD 症状标准。这种设计避免了由于来自不同调查的青少年和成年人在调查方法上的差异而导致的潜在混杂。
共有 133231 名当前饮酒者(在过去一年中至少饮用过 1 次),他们是 2002 年至 2005 年国家药物使用和健康调查的应答者。DSM-IV AUD 标准通过与过去 12 个月内发生的特定症状相关的问题进行评估。因子分析和项目反应理论模型应用于 11 个 AUD 症状标准,以评估不同潜在特征值下症状项目的可能性。
对于总样本和每个性别-年龄组,1 因素模型为 11 个 AUD 标准提供了足够和简约的解释。MIMIC 模型显示,某些标准在性别、年龄和种族/民族之间存在显著的项目偏差。“耐受”、“时间”和“危险使用”的症状标准具有较低的项目阈值(即较低的严重程度)和较低的项目区分度,并且与其他症状明显分离,尤其是在 2 个年龄较小的年龄组(12 至 17 岁和 18 至 25 岁)。“更多量”、“减少”、“戒断”和“法律问题”的项目阈值较高,但一般项目区分度较低,在较高的 AUD 严重程度下,它们往往表现出更大的离散度,尤其是在年龄最小的年龄组(12 至 17 岁)。
本研究的结果不支持在青少年或成年人中分别使用 DSM-IV 诊断酒精滥用和依赖。滥用和依赖标准的严重程度变化为诊断的维度方法提供了支持,这应在 DSM-V 的持续发展中得到考虑。