Bich Claudia, Zenobi Renato
Department of Chemistry and Applied Biosciences, ETH Zürich, CH-8093 Zürich, Switzerland.
Curr Opin Struct Biol. 2009 Oct;19(5):632-9. doi: 10.1016/j.sbi.2009.08.004. Epub 2009 Sep 25.
Mass spectrometry is becoming a more and more powerful tool for investigating protein complexes. Recent developments, based on different ionization techniques, electrospray, desorption/ionization and others are contributing to the usefulness of MS to describe the organization and structure of large non-covalent assemblies.
质谱分析法正日益成为研究蛋白质复合物的一种愈发强大的工具。基于不同电离技术(电喷雾、解吸/电离等)的最新进展,正促使质谱分析法在描述大型非共价组装体的组织和结构方面发挥更大作用。