Newborn Services, Royal Women's Hospital, Melbourne, Australia.
J Pediatr. 2010 Jan;156(1):49-53.e1. doi: 10.1016/j.jpeds.2009.07.013.
To determine the survival rates and neurosensory outcomes of infants born at gestational age 22-27 weeks in the state of Victoria in 2005 and compare theses data with those for similar infants born in the 1990s.
This was a population-based study of all extremely preterm (22-27 weeks' gestational age) live births in Victoria in 2005 free of lethal anomalies and randomly selected term controls. Survival and quality-adjusted survival rates at age 2 years were determined relative to the controls, and results were compared with regional extremely preterm cohorts born in 1991-92 and 1997.
Of 270 very preterm live births in 2005, 172 (63.7%) survived to 2 years, not significantly different from the survival rate of 69.6% for those born in 1997. Rates of severe developmental delay and severe disability were lower than in the very preterm survivors born in 1997. Quality-adjusted survival rates in the extremely preterm cohorts rose from 42.1% in 1991-92 to 55.1% in 1997, but did not increase in 2005 (53.4%).
Survival rates for infants born at 22-27 weeks' gestational age have not increased since the late 1990s, but the neurosensory outcome in survivors has improved.
确定 2005 年在维多利亚州胎龄 22-27 周出生的婴儿的生存率和神经感觉结果，并将这些数据与 20 世纪 90 年代类似婴儿的数据进行比较。
这是一项针对 2005 年维多利亚州所有无致死性畸形的极早产儿（22-27 周胎龄）活产儿的基于人群的研究，并随机选择足月对照儿。相对于对照组，确定了 2 岁时的生存率和调整质量后的生存率，并将结果与 1991-92 年和 1997 年出生的区域性极早产儿队列进行比较。
在 2005 年的 270 例极早产儿活产儿中，有 172 例（63.7%）存活至 2 岁，与 1997 年出生的婴儿的生存率 69.6%无显著差异。严重发育迟缓率和严重残疾率低于 1997 年出生的极早产儿幸存者。极早产儿队列的调整质量后的生存率从 1991-92 年的 42.1%上升到 1997 年的 55.1%，但在 2005 年没有增加（53.4%）。
自 20 世纪 90 年代末以来，胎龄 22-27 周出生的婴儿的生存率没有增加，但幸存者的神经感觉结果有所改善。
