[实验中脂质体对肝脏酪氨酸转氨酶激素诱导作用的影响]
[The effect of liposomes on the hormonal induction of liver tyrosine aminotransferase in an experiment].
作者信息
Galaev Iu V, Zakrevskiĭ V I, Goncharova L V
出版信息
Vopr Med Khim. 1990 Jul-Aug;36(4):6-7.
PMID:1978442
Abstract
Liposomes prevented the hydrocortisone-produced induction of tyrosine aminotransferase in animal liver tissue under conditions of normal state and of alcohol intoxication. The inhibitory effect of liposomes appears to be mainly based on their ability to incorporate into hepatocyte membranes, due to which the membrane permeability towards hydrocortisone was altered.
摘要
在正常状态和酒精中毒状态下，脂质体均可抑制氢化可的松诱导动物肝组织中酪氨酸转氨酶的生成。脂质体的抑制作用似乎主要基于其融入肝细胞膜的能力，由此改变了细胞膜对氢化可的松的通透性。
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