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[半乳糖作用下大鼠肝脏组织中半乳糖激酶诱导的特异性]

[The specificity of galactokinase induction in rat liver tissue under the effect of galactose].

作者信息

Drevich V F, Salganik R I

出版信息

Vopr Med Khim. 1975 Sep-Oct;21(5):503-7.

PMID:3022
Abstract

In liver tissue of rats, a conventional laboratory food of which was substituted for galactose-rich food, the galactokinase activity was increased, but the glucokinase was not affected. In the rats kept on a glucose-rich food the glucokinase (but not the galactokinase) was activated. Hydrocortisone injection induced an increase in tyrosine aminotransferase, but the galactokinase activity was not altered. The data obtained suggest that in rat liver tissue the galactokinase was specifically induced under the effect of galactose. Except for the liver tissue, galactose induced galactokinase in eye crystalline lens; the enzyme activity was not altered in spleen and kidney.

摘要

在大鼠的肝脏组织中,将其常规实验室食物换成富含半乳糖的食物后,半乳糖激酶活性增加,但葡萄糖激酶未受影响。在喂食富含葡萄糖食物的大鼠中,葡萄糖激酶(而非半乳糖激酶)被激活。注射氢化可的松会导致酪氨酸转氨酶增加,但半乳糖激酶活性未改变。所获得的数据表明,在大鼠肝脏组织中,半乳糖激酶是在半乳糖的作用下特异性诱导产生的。除肝脏组织外,半乳糖在眼晶状体中诱导了半乳糖激酶;在脾脏和肾脏中该酶活性未改变。

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