Department of Chemical Engineering, Faculty of Chemical Engineering and Environment Protection, Technical University Gh Asachi of Iasi, Bd D Mangeron, Iasi, Romania.
Int J Antimicrob Agents. 2009 Dec;34(6):534-9. doi: 10.1016/j.ijantimicag.2009.08.008. Epub 2009 Sep 27.
Nanostructured ensembles of silver nanoparticles/zinc-substituted anionic clay matrix (Ag/ZnLDH) were obtained by a simple synthetic route in which reconstruction of the layered clay, synthesis of the silver nanoparticles and their organisation on the clay surface took place in a single step at room temperature. The morphology, composition and phase structure of the prepared powders were characterised by X-ray diffraction, infrared spectroscopy, transmission electron microscopy, X-ray photoelectron spectroscopy and N(2) adsorption. Results showed that the silver-anionic clay nanoarchitecture consists of nanoparticles of silver (average size 7 nm) deposited on the larger nanoparticles of clay (average size 85 nm). The antimicrobial activity was examined by disk diffusion assay and minimal inhibitory concentration determination as a function of x, where x is a controlled variable parameter that represents the length of time since the sample was synthesised. Ag/ZnLDH showed more stable antimicrobial properties than the unsupported nanosized silver.
通过一种简单的合成方法获得了银纳米粒子/锌取代阴离子粘土基质（Ag/ZnLDH）的纳米结构组装体，在该方法中，层状粘土的重构、银纳米粒子的合成及其在粘土表面的组织化在室温下的一步反应中进行。采用 X 射线衍射、红外光谱、透射电子显微镜、X 射线光电子能谱和 N2 吸附对制备粉末的形貌、组成和相结构进行了表征。结果表明，银-阴离子粘土纳米结构由沉积在较大粘土纳米颗粒（平均尺寸 85nm）上的银纳米颗粒（平均尺寸 7nm）组成。抗菌活性通过圆盘扩散试验和最小抑菌浓度测定作为 x 的函数进行了检查，其中 x 是一个受控变量参数，表示自样品合成以来的时间长度。与未负载的纳米银相比，Ag/ZnLDH 显示出更稳定的抗菌性能。
