Department of Neurology and Psychiatry, Tenshi Hospital, Sapporo, Japan.
Epilepsy Behav. 2009 Nov;16(3):491-4. doi: 10.1016/j.yebeh.2009.08.017. Epub 2009 Sep 27.
We investigated the relationship between dissociation and psychogenic nonepileptic seizures (PNES) and evaluated the clinical utility of the Dissociative Experience Scale (DES) in patients with epilepsy. The DES was administered to 30 patients with epilepsy and PNES, 50 patients with epilepsy and no PNES, and 85 nonclinical individuals. Patients with epilepsy and PNES scored significantly higher on the DES (29.3) than patients with epilepsy without PNES (13.5) and nonclinical individuals (11.1). High DES scores (>30) were more frequently observed in patients with epilepsy and PNES (53%) than in patients with epilepsy without PNES (12%) and nonclinical individuals (6%). DES score did not differ significantly with respect to epilepsy-related variables. Neither the frequency nor severity of PNES was significantly associated with the DES score. Our findings confirm some associations between PNES and dissociation in patients with coexisting epilepsy and PNES. The DES could be helpful in determining the tendency to have PNES in patients with epilepsy.
我们研究了分离与心因性非癫痫性发作（PNES）之间的关系，并评估了分离体验量表（DES）在癫痫患者中的临床应用价值。该量表被用于 30 名癫痫伴 PNES 患者、50 名癫痫无 PNES 患者和 85 名非临床个体。癫痫伴 PNES 患者的 DES 评分明显高于癫痫无 PNES 患者（29.3 分比 13.5 分）和非临床个体（11.1 分）。在癫痫伴 PNES 患者中（53%），高 DES 评分（>30）比癫痫无 PNES 患者（12%）和非临床个体（6%）更为常见。DES 评分与癫痫相关变量无显著差异。PNES 的频率和严重程度与 DES 评分均无显著相关性。我们的研究结果证实了共存癫痫和 PNES 患者中 PNES 与分离之间的某些关联。DES 可能有助于确定癫痫患者发生 PNES 的倾向。
