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心因性非癫痫性发作的临床特征:中国西南地区 64 例研究。

Clinical features of psychogenic nonepileptic seizures: a study of 64 cases in southwest China.

机构信息

Department of Neurology, West China Hospital of Sichuan University, Chengdu, Sichuan, People's Republic of China.

出版信息

Epilepsy Behav. 2010 Mar;17(3):408-11. doi: 10.1016/j.yebeh.2010.01.003. Epub 2010 Feb 9.

DOI:10.1016/j.yebeh.2010.01.003
PMID:20149757
Abstract

This article describes the clinical features of psychogenic nonepileptic seizures (PNES) in people in southwest China. Patients with a confirmed diagnosis of pure PNES by video/EEG monitoring were retrospectively reviewed. A total of 64 patients with PNES were included, 32 (50%) of whom were male. Twenty (31.3%) patients had previously been misdiagnosed and treated for epilepsy. Psychological trauma and head injuries were considered antecedent traumatic factors. A history of abuse was rare. The PNES cases were divided into three subtypes: psychogenic minor motor seizures, psychogenic major motor seizures, and unresponsive seizures. Age at onset was identified as a predictor of prognosis. The results of this study demonstrated a higher prevalence of PNES in males compared with previous studies. The semiology of PNES in China is similar to that in Western countries. Classification of semiology may be helpful in the differential diagnosis of PNES.

摘要

本文描述了中国西南地区人群中精神性非癫痫性发作(PNES)的临床特征。对经视频/EEG 监测确诊为单纯 PNES 的患者进行回顾性分析。共纳入 64 例 PNES 患者,其中 32 例(50%)为男性。20 例(31.3%)患者曾被误诊和癫痫治疗。心理创伤和头部外伤被认为是先前的创伤因素。虐待史很少见。PNES 病例分为 3 种亚型:精神性轻度运动发作、精神性重度运动发作和无反应性发作。发病年龄是预后的预测因素。本研究结果表明,PNES 在男性中的患病率高于以往研究。中国的 PNES 临床表现与西方国家相似。半表型分类可能有助于 PNES 的鉴别诊断。

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