Departmentof Nutrition and Food Science, University of the Basque Country, Paseo de la Universidad, 7, ES-01006 Vitoria, Spain.
Ann Nutr Metab. 2009;54(4):313-20. doi: 10.1159/000242441. Epub 2009 Sep 29.
To examine the effect of early menarche (EM) on adolescent body composition and fat distribution, and to explore the possible contribution of birth weight (BW) to this relationship.
From the cross-sectional AVENA study, 788 girls (aged 13-18.5 years) were selected. Post-menarcheal body composition was estimated by anthropometric methods.
BW Z-score was associated with age at menarche (beta = 0.496, p < 0.001). EM (age of menarche <12 years) adolescents were shorter, had a higher body mass index (BMI), fat free mass index (FFMI), fat mass index (FMI) and waist circumference (all p < 0.01). BW was associated with height (p < 0.001), BMI Z-score (p < 0.01), FFMI (p < 0.01) and FMI (p < 0.05). These relationships did not change when the analysis was controlled for age of menarche. Height and FFM were lower in EM (p < 0.01), but these effects seem to be due to the BW (p < 0.01).
EM was strongly associated with unhealthy body composition in female adolescents, but these relationships seem to be due to the programming effect of BW.
研究目的在于探讨初潮（EM）对青少年身体成分和脂肪分布的影响，并探索出生体重（BW）对这种关系的可能贡献。
从横断面 AVENA 研究中，选择了 788 名女孩（年龄 13-18.5 岁）。通过人体测量方法估计青春期后身体成分。
BW Z 分数与初潮年龄（β=0.496，p<0.001）相关。EM（初潮年龄<12 岁）青少年更矮，体重指数（BMI）、去脂体重指数（FFMI）、脂肪量指数（FMI）和腰围更高（均 p<0.01）。BW 与身高（p<0.001）、BMI Z 分数（p<0.01）、FFMI（p<0.01）和 FMI（p<0.05）相关。当分析控制初潮年龄时，这些关系没有改变。EM 组身高和 FFM 较低（p<0.01），但这些影响似乎归因于 BW（p<0.01）。
EM 与女性青少年不健康的身体成分密切相关，但这些关系似乎归因于 BW 的编程效应。
