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辐射风险与成像选择。

Risk of radiation and choice of imaging.

作者信息

Herfarth Hans, Palmer Lena

机构信息

Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, NC 27599, USA.

出版信息

Dig Dis. 2009;27(3):278-84. doi: 10.1159/000228561. Epub 2009 Sep 24.

Abstract

Radiological imaging plays an important role in the diagnosis and management of patients with inflammatory bowel diseases (IBD). The barium or contrast techniques enteroclysis (SBE) and small bowel follow through (SBFT) are still the mainstays in small bowel imaging. However, abdominal CT and MRI, including enteroclysis, have comparable sensitivity and specificity in detecting intestinal pathologies and have gained in popularity over conventional techniques. The cancer risk associated with diagnostic procedures employing radiation has been receiving increasing attention over the last few years. The cumulative exposure to ionizing radiation may be a specific concern in young patients with IBD, who are more susceptible than adults to the risks of ionizing radiation. Substantial exposure to radiation seems to be mainly caused by CT examinations of the abdomen. For that reason, imaging methods such as MRI or ultrasound should be considered first when debating between alternative imaging strategies, particularly in young IBD patients. The major drawbacks of MRI are its limited availability and greater costs compared to CT. Moreover, the diagnostic accuracy of abdominal ultrasound is clearly operator dependent, which limits the range of its applications. In light of these concerns, diagnostic imaging studies using radiation will continue to play an important role in the evaluation of patients with IBD. Therefore, we need to develop low-radiation imaging protocols or improve access to MRI imaging procedures. We also need to identify subsets of IBD patients who are at greater risk of a significant lifetime exposure to radiation and develop methods to monitor their radiation exposure rate.

摘要

放射影像学在炎症性肠病(IBD)患者的诊断和管理中发挥着重要作用。钡剂或对比剂技术小肠灌肠造影(SBE)和小肠钡剂通过造影(SBFT)仍是小肠成像的主要方法。然而,腹部CT和MRI,包括小肠灌肠造影,在检测肠道病变方面具有相当的敏感性和特异性,并且比传统技术更受欢迎。在过去几年中,与使用辐射的诊断程序相关的癌症风险受到了越来越多的关注。对于年轻的IBD患者,电离辐射的累积暴露可能是一个特别令人担忧的问题,他们比成年人更容易受到电离辐射风险的影响。大量的辐射暴露似乎主要是由腹部CT检查引起的。因此,在讨论替代成像策略时,应首先考虑MRI或超声等成像方法,特别是在年轻的IBD患者中。MRI的主要缺点是其可用性有限,且与CT相比成本更高。此外,腹部超声的诊断准确性明显依赖于操作者,这限制了其应用范围。鉴于这些问题,使用辐射的诊断成像研究将继续在IBD患者的评估中发挥重要作用。因此,我们需要制定低辐射成像方案或改善MRI成像程序的可及性。我们还需要确定那些一生中面临显著辐射暴露风险更高的IBD患者亚组,并开发监测他们辐射暴露率的方法。

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