Wylegała Edward, Nowińska Anna
Department of Ophthalmology, District Railway Hospital, Katowice - Poland.
Eur J Ophthalmol. 2009 Sep-Oct;19(5):723-8. doi: 10.1177/112067210901900506.
To evaluate the usefulness of anterior segment optical coherence tomography (OCT) in diagnosis, choosing the treatment method, and monitoring the treatment outcomes in Descemet membrane detachment DMD).
We retrospectively reviewed the clinical data for 14 eyes of 13 patients: 8 eyes with DMD after cataract surgery, 2 eyes after deep anterior lamellar keratoplasty (DALK), 2 eyes of 1 patient with Ehlers-Danlos type VI syndrome, 1 eye after contusion, and 1 eye with spontaneous corneal edema of unknown origin. We used OCT to confirm or make the diagnosis, evaluate the configuration of detachment, and monitor treatment results.
DMD was diagnosed in 12 eyes, based on the slit lamp examination. In 2 eyes, because of a very hazy view due to corneal edema, DMD was diagnosed based on OCT findings. We chose the treatment method based on DMD configuration evaluated by OCT examination. Eight eyes were treated conservatively and 6 eyes underwent intracameral air injection with additional ab externo stab incisions. In 12 eyes, Descemet membrane reattached successfully. In 2 eyes of 1 patient with Ehlers-Danlos syndrome, the detachment remained, but corneal thickness had decreased. After anterior chamber air tamponade, we observed the decrease of corneal thickness within 7 days.
OCT is useful in precise evaluation of DMD configuration and choosing the treatment method, but has a very limited role in diagnosis and monitoring the treatment results, where the clinical examination is the most important indicating factor.
评估眼前节光学相干断层扫描(OCT)在诊断、选择治疗方法及监测后弹力层脱离(DMD)治疗效果方面的作用。
我们回顾性分析了13例患者14只眼的临床资料:白内障术后发生DMD的有8只眼,深板层角膜移植术(DALK)后2只眼,1例患有Ⅵ型埃勒斯-当洛综合征患者的2只眼,挫伤后1只眼,不明原因自发性角膜水肿1只眼。我们使用OCT来确诊或做出诊断、评估脱离的形态并监测治疗结果。
根据裂隙灯检查,12只眼诊断为DMD。2只眼因角膜水肿导致视野非常模糊,基于OCT检查结果诊断为DMD。我们根据OCT检查评估的DMD形态选择治疗方法。8只眼采用保守治疗,6只眼进行前房内空气注射并额外做外路穿刺切口。12只眼中,后弹力层成功复位。1例患有埃勒斯-当洛综合征患者的2只眼脱离仍存在,但角膜厚度有所下降。前房空气填塞后,我们观察到7天内角膜厚度下降。
OCT有助于精确评估DMD形态并选择治疗方法,但在诊断和监测治疗效果方面作用非常有限,临床检查是最重要的指示因素。