Naehle Claas P, Müller Andreas, Willinek Winfried A, Meyer Carsten, Hestermann Tobias, Gieseke Juergen, Schild Hans, Thomas Daniel
Department of Radiology, University of Bonn, Germany.
J Magn Reson Imaging. 2009 Oct;30(4):809-16. doi: 10.1002/jmri.21919.
To compare a high-resolution, ECG-gated, motion-compensated, steady-state magnetic resonance angiography (SS-MRA) of the thoracic vasculature to standard first-pass MRA (FP-MRA) using a blood-pool contrast agent (gadofosveset trisodium).
In all, 25 patients >or=18 years with congenital or acquired disease of the thoracic vasculature, who underwent both FP-MRA and SS-MRA, were retrospectively identified. Diameters of left superior pulmonary vein (LSPV), left pulmonary artery (LPA), and aortic arch (AA) were measured. Image quality for LSPV, LPA, AA, coronary ostia, and coronary sinus were assessed. Vessel sharpness of LPA and LSPV and contrast ratio (CR) of LSPV, LPA, and AA were calculated.
SS-MRA yielded significantly higher image quality for all vessels, and significantly higher vessel sharpness for LSPV and LPA compared to the FP-MRA. SS-MRA revealed lower intra- and interobserver variability for vessel diameters compared with the FP-MRA. The FP-MRA showed higher CR compared to the SS-MRA.
Motion-compensated high-resolution SS-MRA of the thoracic vasculature using gadofosveset trisodium offers superior image quality compared to standard FP-MRA. Although SS-MRA delivers no dynamic information it may prove specifically helpful as an add-on to FP-MRA for imaging of small vascular structures.
使用血池造影剂（钆布醇三钠），将胸部血管的高分辨率、心电图门控、运动补偿稳态磁共振血管造影（SS-MRA）与标准的首次通过MRA（FP-MRA）进行比较。
回顾性纳入25例年龄≥18岁、患有先天性或后天性胸部血管疾病且接受了FP-MRA和SS-MRA检查的患者。测量左上肺静脉（LSPV）、左肺动脉（LPA）和主动脉弓（AA）的直径。评估LSPV、LPA、AA、冠状动脉口和冠状窦的图像质量。计算LPA和LSPV的血管清晰度以及LSPV、LPA和AA的对比率（CR）。
与FP-MRA相比，SS-MRA对所有血管的图像质量显著更高，对LSPV和LPA的血管清晰度也显著更高。与FP-MRA相比，SS-MRA显示血管直径的观察者内和观察者间变异性更低。与SS-MRA相比，FP-MRA显示出更高的CR。
使用钆布醇三钠的运动补偿高分辨率胸部血管SS-MRA与标准FP-MRA相比，具有更高的图像质量。尽管SS-MRA不提供动态信息，但作为FP-MRA的补充用于小血管结构成像可能特别有用。
