Browne Andrew W, Rust Michael J, Jung Wooseok, Lee Se Hwan, Ahn Chong H
Microsystems and BioMEMS Laboratory, Department of Electrical and Computer Engineering, University of Cincinnati, Cincinnati, OH 45221, USA.
Lab Chip. 2009 Oct 21;9(20):2941-6. doi: 10.1039/b903755a. Epub 2009 Jul 14.
In this work, a new method of rapidly fabricating thermopolymer and elastomer microfluidic channels has been developed and characterized for production of microfluidics with fixed aspect ratio and 3D tapered channels. A unique way to attain a desired channel depth by simply altering channel width is demonstrated. This rapid prototyping method is compatible with replication methods such as injection molding, hot embossing and elastomer casting and offers the ability to fabricate multiple channel depths (5 microm-1 mm) simultaneously in a single lithographic step. This method yields facile fabrication of 3-dimensionally tapered channels and polymer lab chips.
在这项工作中，已开发并表征了一种快速制造热聚合物和弹性体微流体通道的新方法，用于生产具有固定纵横比和三维锥形通道的微流体。展示了一种通过简单改变通道宽度来获得所需通道深度的独特方法。这种快速成型方法与诸如注塑成型、热压印和弹性体浇铸等复制方法兼容，并能够在单个光刻步骤中同时制造多个通道深度（5微米至1毫米）。该方法可轻松制造三维锥形通道和聚合物实验室芯片。
