Tony Anthony, Badea Ildiko, Yang Chun, Liu Yuyi, Wells Garth, Wang Kemin, Yin Ruixue, Zhang Hongbo, Zhang Wenjun
Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, SK S7N 5A9, Canada.
College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Polymers (Basel). 2023 Apr 18;15(8):1926. doi: 10.3390/polym15081926.
This paper presents a comprehensive review of the literature for fabricating PDMS microfluidic devices by employing additive manufacturing (AM) processes. AM processes for PDMS microfluidic devices are first classified into (i) the direct printing approach and (ii) the indirect printing approach. The scope of the review covers both approaches, though the focus is on the printed mold approach, which is a kind of the so-called replica mold approach or soft lithography approach. This approach is, in essence, casting PDMS materials with the mold which is printed. The paper also includes our on-going effort on the printed mold approach. The main contribution of this paper is the identification of knowledge gaps and elaboration of future work toward closing the knowledge gaps in fabrication of PDMS microfluidic devices. The second contribution is the development of a novel classification of AM processes from design thinking. There is also a contribution in clarifying confusion in the literature regarding the soft lithography technique; this classification has provided a consistent ontology in the sub-field of the fabrication of microfluidic devices involving AM processes.
本文对采用增材制造（AM）工艺制造聚二甲基硅氧烷（PDMS）微流控器件的文献进行了全面综述。用于制造PDMS微流控器件的增材制造工艺首先分为：（i）直接打印法和（ii）间接打印法。尽管综述重点关注打印模具法（它是一种所谓的复制模具法或软光刻法），但综述范围涵盖了这两种方法。这种方法本质上是用打印出来的模具浇铸PDMS材料。本文还包括我们在打印模具法方面正在进行的工作。本文的主要贡献在于识别了知识空白，并阐述了为填补PDMS微流控器件制造方面的知识空白而开展的未来工作。第二个贡献是从设计思维角度开发了一种新颖的增材制造工艺分类方法。此外，本文还有助于澄清文献中关于软光刻技术的混淆之处；这种分类方法在涉及增材制造工艺的微流控器件制造子领域提供了一个一致的本体论。
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