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内源性阿片肽与行为:2008 年。

Endogenous opiates and behavior: 2008.

机构信息

Department of Psychology and Neuropsychology Doctoral Sub-Program, Queens College, City University of New York, 65-30 Kissena Blvd, Flushing, NY 11367, United States.

出版信息

Peptides. 2009 Dec;30(12):2432-79. doi: 10.1016/j.peptides.2009.09.027. Epub 2009 Sep 28.

DOI:10.1016/j.peptides.2009.09.027
PMID:19793543
Abstract

This paper is the 31st consecutive installment of the annual review of research concerning the endogenous opioid system. It summarizes papers published during 2008 that studied the behavioral effects of molecular, pharmacological and genetic manipulation of opioid peptides, opioid receptors, opioid agonists and opioid antagonists. The particular topics that continue to be covered include the molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors related to behavior (Section 2), and the roles of these opioid peptides and receptors in pain and analgesia (Section 3); stress and social status (Section 4); tolerance and dependence (Section 5); learning and memory (Section 6); eating and drinking (Section 7); alcohol and drugs of abuse (Section 8); sexual activity and hormones, pregnancy, development and endocrinology (Section 9); mental illness and mood (Section 10); seizures and neurologic disorders (Section 11); electrical-related activity and neurophysiology (Section 12); general activity and locomotion (Section 13); gastrointestinal, renal and hepatic functions (Section 14); cardiovascular responses (Section 15); respiration and thermoregulation (Section 16); and immunological responses (Section 17).

摘要

本文是关于内源性阿片肽系统的年度研究综述的第 31 期连载。它总结了 2008 年发表的研究论文,这些论文研究了分子、药理学和遗传操作对阿片肽、阿片受体、阿片激动剂和阿片拮抗剂的行为影响。继续涵盖的特定主题包括与行为相关的内源性阿片肽及其受体的分子-生化效应和神经化学定位研究(第 2 节),以及这些阿片肽和受体在疼痛和镇痛中的作用(第 3 节);应激和社会地位(第 4 节);耐受和依赖(第 5 节);学习和记忆(第 6 节);饮食和饮水(第 7 节);酒精和滥用药物(第 8 节);性活动和激素、怀孕、发育和内分泌(第 9 节);精神疾病和情绪(第 10 节);癫痫和神经障碍(第 11 节);与电相关的活动和神经生理学(第 12 节);一般活动和运动(第 13 节);胃肠道、肾脏和肝脏功能(第 14 节);心血管反应(第 15 节);呼吸和体温调节(第 16 节);和免疫反应(第 17 节)。

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