Department of Obstetrics and Gynaecology, University Hospital of the West Indies, Mona, Kingston, Jamaica.
Int J Gynaecol Obstet. 2010 Jan;108(1):65-8. doi: 10.1016/j.ijgo.2009.08.008.
To determine whether cocoa butter cream is effective in preventing striae gravidarum.
This randomized, double-blind, placebo-controlled trial enrolled 300 pregnant women: 150 women received cocoa butter cream and 150 women received a placebo cream. The women were followed-up from 16 weeks of pregnancy to delivery to assess the development of striae gravidarum. Maternal height, weight, and abdominal girth were recorded at each visit. After delivery the placenta was weighed, and anthropometry and Apgar scores of the neonate were recorded.
The 2 groups had similar clinical parameters at booking. Striae gravidarum developed in 44% of patients using cocoa butter cream compared with 55% of those using placebo; the difference was not significant (chi(2)=2.8, df(1), P=0.09). Striae gravidarum were more common among younger women and those with large neonates. However, no relationship was found between development of striae and body mass index.
Cocoa butter cream does not prevent striae gravidarum. In Afro-Caribbean women, development of striae is related to young age of the mother and large neonates.
探讨可可脂乳膏预防妊娠纹的效果。
本随机、双盲、安慰剂对照试验共纳入 300 名孕妇，150 名孕妇使用可可脂乳膏，150 名孕妇使用安慰剂乳膏。从妊娠 16 周到分娩对孕妇进行随访，以评估妊娠纹的发生情况。每次就诊时记录孕妇的身高、体重和腹围。分娩后测量胎盘重量，并记录新生儿的人体测量学和阿普加评分。
两组在初诊时的临床参数相似。使用可可脂乳膏的患者中有 44%出现妊娠纹，而使用安慰剂的患者中有 55%出现妊娠纹，差异无统计学意义（chi(2)=2.8，df(1)，P=0.09）。妊娠纹在年轻女性和新生儿较大的女性中更为常见。然而，妊娠纹的发生与体重指数之间没有关系。
可可脂乳膏不能预防妊娠纹。在非裔加勒比妇女中，妊娠纹的发生与母亲年龄较小和新生儿较大有关。
