Rahman Ifad, Narasimhan Kanakasabai, Aziz Shahid, Owens William
Division of Internal Medicine, University of South Carolina School of Medicine, Columbia, South Carolina, USA.
Am J Med Sci. 2009 Nov;338(5):433-4. doi: 10.1097/MAJ.0b013e3181b7f2a3.
The majority of reported cases of gasoline intoxication involves inhalation or percutaneous absorption. Data are scarce on complications and outcomes after gasoline poisoning by oral ingestion. The major cause of mortality and morbidity associated with the ingestion of gasoline is related to pulmonary aspiration. Despite the high frequency of the ingestions, there is little documentation of nonpulmonary toxic effects of gasoline. After ingestion, the principal toxicity is aspiration pneumonia, but any documented extra pulmonary manifestations of this condition may be important in the overall management of these patients. We are reporting a rare case of pancytopenia along with aspiration pneumonia and multisystem organ failure in a 58-year-old male after prolonged intentional ingestion of gasoline. To our knowledge, this is the only reported case of gasoline toxicity causing pancytopenia.
大多数报告的汽油中毒病例涉及吸入或经皮吸收。关于经口摄入汽油中毒后的并发症和结局的数据很少。与摄入汽油相关的死亡和发病的主要原因与肺吸入有关。尽管摄入汽油的情况很常见,但关于汽油非肺部毒性作用的文献却很少。摄入后,主要毒性是吸入性肺炎,但这种情况的任何已记录的肺外表现可能对这些患者的整体管理很重要。我们报告了一例罕见病例,一名58岁男性在长期故意摄入汽油后出现全血细胞减少症,同时伴有吸入性肺炎和多系统器官衰竭。据我们所知,这是唯一一例报告的汽油毒性导致全血细胞减少症的病例。