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在厄瓜多尔人群中进行的遗传毒性研究。

Genotoxicity studies performed in the ecuadorian population.

作者信息

Paz-Y-Miño César, Cumbal Nadia, Sánchez María Eugenia

机构信息

Instituto de Investigaciones Biomédicas, Facultad de Ciencias de la Salud, Universidad de las Américas, Ave. de los Granados y Colimes Quito, 1712842, Ecuador.

出版信息

Mol Biol Int. 2012;2012:598984. doi: 10.1155/2012/598984. Epub 2012 Feb 16.

Abstract

Genotoxicity studies in Ecuador have been carried out during the past two decades. The focuses of the research were mainly the area of environmental issues, where the populations have been accidentally exposed to contaminants and the area of occupational exposure of individuals at the workplace. This paper includes studies carried out in the population of the Amazon region, a zone known for its rich biodiversity as well as for the ecological damage caused by oil spills and chemical sprayings whose consequences continue to be controversial. Additionally, we show the results of studies comprised of individuals occupationally exposed to toxic agents in two very different settings: flower plantation workers exposed to pesticide mixtures and X-ray exposure of hospital workers. The results from these studies confirm that genotoxicity studies can help evaluate current conditions and prevent further damage in the populations exposed to contaminants. As such, they are evidence of the need for biomonitoring employers at risk, stricter law enforcement regarding the use of pesticides, and increasingly conscientious oil extraction activities.

摘要

过去二十年来,厄瓜多尔开展了遗传毒性研究。研究重点主要在环境问题领域,当地居民意外接触污染物,以及工作场所个人的职业暴露领域。本文涵盖了在亚马逊地区人群中开展的研究,该地区以其丰富的生物多样性以及石油泄漏和化学喷洒造成的生态破坏而闻名,其后果仍存在争议。此外,我们展示了在两种截然不同环境下职业接触有毒物质的个体研究结果:接触农药混合物的花卉种植工人和医院工作人员的X射线照射。这些研究结果证实,遗传毒性研究有助于评估当前状况,并防止接触污染物人群受到进一步损害。因此,它们证明了有必要对处于风险中的雇主进行生物监测,加强对农药使用的执法力度,以及提高石油开采活动的自觉性。

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