Mahmoodpoor Ata, Soleimanpour Hassan, Hamishehkar Hadi
Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Acta Med Iran. 2012;50(12):846-8.
Hydrocarbons are ubiquitous in daily life and include plant and animal fats, alcohols, solvents, natural gas, petroleum derivates. Majority of intoxication reports of hydrocarbons are due to inhalation or ingestion, but there is few reports about intravenous injection of gasoline. We report a 58 year-old man who injected gasoline intravenously for suicide. He developed soft tissue necrosis of forearm and bilateral pulmonary infiltration. He underwent fasciotomy and extensive debridement of necrotic tissues, at the operation room. He was intubated and mechanically ventilated because of acute lung injury. He developed acute kidney injury after 2 days. These symptoms seem to be due to extravasation of gasoline from vessels which lead to inflammation, cell damage and organ failure. The patient developed multi organ failure which unfortunately did not respond to our treatment and he died at day 21. Management of gasoline intoxication depends on the rout of exposure. Like other types of toxications, intravenous toxication has pulmonary involvement, however in this case we had multiple organ involvement. It seems that in such cases we should consider early end organ targeted therapy to stop the future organ failure.
碳氢化合物在日常生活中无处不在，包括动植物脂肪、酒精、溶剂、天然气、石油衍生物。大多数碳氢化合物中毒报告是由于吸入或摄入，但关于静脉注射汽油的报告很少。我们报告一名58岁男子为自杀而静脉注射汽油。他出现了前臂软组织坏死和双侧肺部浸润。他在手术室接受了筋膜切开术和坏死组织的广泛清创术。由于急性肺损伤，他接受了插管和机械通气。两天后他出现了急性肾损伤。这些症状似乎是由于汽油从血管外渗导致炎症、细胞损伤和器官衰竭。患者出现多器官功能衰竭，不幸的是对我们的治疗没有反应，于第21天死亡。汽油中毒的处理取决于接触途径。与其他类型的中毒一样，静脉中毒会累及肺部，然而在这种情况下，我们有多个器官受累。在这种情况下，似乎我们应该考虑早期针对终末器官的靶向治疗，以阻止未来的器官衰竭。
