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应用 Ceraver 可吸收β-磷酸三钙楔形骨片行胫骨撑开楔形截骨术治疗严重内翻畸形。

Opening wedge tibial osteotomy for large varus deformity with Ceraver resorbable beta tricalcium phosphate wedges.

机构信息

Hôpital Henri Mondor, University Paris XII, 94010 Creteil, France.

出版信息

Int Orthop. 2010 Feb;34(2):191-9. doi: 10.1007/s00264-009-0875-1. Epub 2009 Oct 1.

Abstract

The results in 53 knees that had been treated by proximal tibial opening-wedge osteotomy for large varus deformity and osteoarthritis of the medial compartment were evaluated after a mean length of follow-up of ten years (range, 8-12 years). We used a porous beta-tricalcium phosphate (beta-TCP) wedge because it is resorbable and osteoinductive. All osteotomies were completely consolidated and complete osseointegration of the remnant of the beta-TCP wedge took place. However, after a mean maximum follow-up of ten years none of the cases showed complete resorption. After ten years, 40 (81%) of the 53 knees had an excellent or good result, and in 13 knees there was recurrent pain for which six had an arthroplasty. Although the results deteriorated with time, time was not the only determinant of the result. Alignment, measured as the hip-knee-ankle angle on radiographs of the whole limb that were made with the patient bearing weight, was also a determinant of long-term results. The best results were obtained in the knees that had a hip-knee-ankle angle of 183-186 degrees. In these knees, there was no pain and no progression of the arthrosis in either the medial or the lateral tibiofemoral compartment. Of the three knees that had an angle of more than 186 degrees, all five had progressive degenerative changes in the lateral compartment. In the undercorrected knees (an angle of less than 183 degrees), the results were less satisfactory, and there was a tendency toward recurrence of the varus deformity and progression of the arthritis of the medial compartment. However, when the correction was insufficient the deterioration was slow. Therefore, proximal tibial osteotomy is a very suitable operation even for patients who have gonarthrosis of the medial compartment and a large varus deformity. Although, a rigidly standardised and precise operative technique is required as well as accurate radiographic measurements of the mechanical axis of the limb because exact postoperative alignment is the prerequisite for the longest possible period of relief of symptoms after osteotomy, and this exact alignment is difficult to obtain for patients with large varus deformity.

摘要

53 例膝关节因大的内翻畸形和内侧间室骨关节炎行胫骨近端开口楔形截骨术治疗,平均随访 10 年(8-12 年)后进行评估。我们使用多孔β-磷酸三钙(β-TCP)楔形物,因为它可吸收且具有成骨诱导性。所有截骨均完全愈合,β-TCP 楔形物的残端完全实现了骨整合。然而,平均 10 年最大随访后,没有一个病例显示完全吸收。10 年后,53 例膝关节中有 40 例(81%)结果为优或良,13 例出现复发性疼痛,其中 6 例接受了关节置换。尽管结果随时间恶化,但时间并不是结果的唯一决定因素。在负重下肢全长 X 线片上测量的髋膝踝角(HKA)也是长期结果的决定因素。HKA 为 183-186 度的膝关节获得最佳结果。在这些膝关节中,没有疼痛,内侧和外侧胫股间室的关节炎均无进展。在 HKA 大于 186 度的 3 例膝关节中,所有 5 例外侧间室均有进行性退行性改变。在矫正不足的膝关节(HKA 小于 183 度)中,结果不太满意,存在内翻畸形复发和内侧间室关节炎进展的趋势。然而,当矫正不足时,退变进展缓慢。因此,胫骨近端截骨术是一种非常适合的手术,即使对于内侧间室骨关节炎和大的内翻畸形的患者也是如此。尽管需要严格标准化和精确的手术技术以及下肢机械轴的精确放射学测量,但术后精确的对线是截骨术后最长时间缓解症状的前提,对于大的内翻畸形患者,很难获得这种精确的对线。

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